Sort   by:  
 Page size 
TranscriptomicsActivity of SigB Modulates Virulence Gene Expression in a Murine Staphylococcus aureus Infection Model but Does Not Influence the Host Kidney Gene Expression
Background. Infections caused by Staphylococcus aureus are associated with significant morbidity and mortality and are an increasing threat not only in hospital settings. The expression of the staphylococcal virulence factor repertoire is known to be affected by the alternative sigma factor B (SigB...
ORGANISM(S): Mus musculus 
2011-10-23 | E-GEOD-28540 | biostudies-arrayexpress
TranscriptomicsTranscriptome-driven constraint-based modelling reveals metabolic targets for ovarian cancer
OV56 ovarian cancer cell line treated with siTPI1 (siRNA targeted against triose phosphate isomerase 1) and the following negative controls: NTsiRNA (non-targeting siRNA), transfection reagent only and untreated. Experiment designed to assess the effect of TPI1 gene knockdown on OV56 gene expression...
ORGANISM(S): Homo sapiens 
2026-04-09 | E-MTAB-16770 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of mouse bone marrow-derived macrophages (BMDMs) upon treatment with the S-palmitoylation inhibitor 2BP and/or myelin
The formation of inflammatory foamy macrophages hinders brain repair in multiple sclerosis. Therefore, the phenotype of the macrophages can determine the repair status of brain lesions. Here, we established the impact of the general S-palmitoylation inhibitor 2BP on the phenotype of bone marrow-deri...
ORGANISM(S): Mus musculus 
2026-10-27 | E-MTAB-15390 | biostudies-arrayexpress
TranscriptomicsFate and State Transitions during Human Blood Vessel Organoid Development: Time Course
Human blood vessel organoids (hBVOs) derived from human pluripotent stem cells have emerged as a novel system to understand human vascular development, model disorders, and develop regenerative therapies. However, it was unclear which molecular states constitute hBVOs and how cells differentiate and...
ORGANISM(S): Homo sapiens 
2025-03-21 | E-MTAB-14807 | biostudies-arrayexpress
Sort   by:  
 Page size