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MetabolomicsIdentification of potential sepsis biomarkers in burn injury conditions.
Not available
ORGANISM(S): Mus musculus 
ST001101 | MetabolomicsWorkbench
MetabolomicsEnhancing sensory quality of heat-not-burn tobacco via bioaugmentation with Cytobacillus oceanisediminis C4 and Amylase

Tobacco fermentation is a crucial process for improving tobacco quality by reducing undesirable substances. In this study, an enzyme–microbe combined fermentation strategy was established and evaluated. Cytobacillus oceanisediminis C4 combined with amylase pretreatment was applied in the fermenta...

2025-12-26 | MTBLS13570 | MetaboLights
TranscriptomicsTranscription profiling time series of Rattus norvegicus liver samples following burn injury
Type of experiment: Comparison of liver samples between sham (control) and 20% TBSA (total burn surface area) burn rats collected at 1h, 4h, 8h, and 24h. Experimental factors: Burn injury and time; Experiment design: All experimental liver samples collected after 1h, 4h, 8h, and 24h after burn inju...
ORGANISM(S): Rattus norvegicus 
2007-10-11 | E-GEOD-802 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat liver samples from individuals subjected to burn injury or cecal ligation and puncture
The experimental design included three biological replicates for each of the three conditions: Sham-Sham, Sham-CLP and burn-CLP. Liver samples were collected from the rats and the total RNA was analyzed on a Affymetrix RAE230A chip. No technical replicates were included in the study
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-1781 | biostudies-arrayexpress
TranscriptomicsA large-scale clinical study of gene expression response to severe burn injury
To understand the age-dependent response to burn injury, blood samples from pediatric and adult patients were collected at different times after severe burn injury. Gene expression was measured using Affymetrix U133 Plus 2.0 arrays for both patient samples and healthy controls. Time points were binn...
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-19743 | biostudies-arrayexpress
MetabolomicsMulti-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke
Cigarette smoke (CS) causes adverse health effects and leads to the development of respiratory disease (chronic obstructive pulmonary disease), cardiovascular disease, and cancer. To reduce the risk of smokers developing smoking-related diseases, Philip Morris International is developing modified ri...
2020-04-25 | MTBLS158 | MetaboLights
ProteomicsPediatric burn blister fluid LC-MS/MS SWATH
Blister fluid (BF) is a novel and viable research matrix for burn injury study, which can reflect both systemic and local micro-environmental responses. The protein abundance in BF from different burn severities were initially observed using a 2D SDS-PAGE approach. Subsequently, a quantitative data ...
ORGANISM(S): Homo sapiens (Human) 
2018-12-21 | PXD011102 | Pride
Proteomics Swath Blister fluid Time to re-epithelialization Burn injury Burn depth 
ProteomicsTemporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.
Introduction Severe injury, including burn trauma, leads to profound immune dysfunction, yet the mechanisms driving these changes remain incompletely defined. This lack of understanding has hindered efforts to modulate the immune response effectively. Additionally, a clear biomarker profile to guide...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-21 | PXD062615 | Pride
Protein cargo Extracellular vesicles Macrophages Burn injury Thermal injury Burn injury 
ProteomicsIdentification of plasma extracellular vesicle biomarkers after burn injury
Severe burn injury is a one of the most devastating forms of trauma with over 1.1 million burns each year requiring medical attention in the United States. Deaths from burn injury are commonly caused by immune-related sequelae such as pneumonia, organ failure and other opportunistic bacterial infect...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-16 | PXD028515 | Pride
Microvesicle Proteomics Extracellular vesicles Label-free quantitation 
UnknownPeritraumatic Vitamin D Levels Predict Chronic Pain Severity and Contribute to Racial Differences in Pain Outcomes Following Major Thermal Burn Injury.
Not available
S-EPMC8921735 | biostudies-literature
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