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TranscriptomicsMicroarray transcriptomic profiling of patients with sepsis due to faecal peritonitis and pneumonia to identify shared and distinct aspects of the transcriptomic response (validation cohort)
We assayed leukocyte global gene expression for a prospective discovery cohort of 106 adult patients admitted to UK intensive care units with sepsis due to community acquired pneumonia or faecal peritonitis. We assigned all samples to sepsis response signature groups after performing unsupervised an...
ORGANISM(S): Homo sapiens 
2017-05-01 | E-MTAB-5274 | biostudies-arrayexpress
TranscriptomicsMicroarray transcriptomic profiling of patients with sepsis due to faecal peritonitis and pneumonia to identify shared and distinct aspects of the transcriptomic response (discovery cohort)
We assayed leukocyte global gene expression for a prospective validation cohort of 221 adult patients admitted to UK intensive care units with sepsis due to community acquired pneumonia or faecal peritonitis. 10 samples from patients scheduled for elective cardiac surgery were also assayed as non-se...
ORGANISM(S): Homo sapiens 
2017-05-01 | E-MTAB-5273 | biostudies-arrayexpress
TranscriptomicsSRS endotype assignment of septic shock patients from the VANISH randomised trial
The aim of the experiment was to assign patients enrolled in the VANISH randomised trial to sepsis response signature (SRS) endotypes based on a previously published gene expression signature, in order to test for differential responses to treatment. VANISH was a double-blind randomised clinical tri...
ORGANISM(S): Homo sapiens 
2022-07-12 | E-MTAB-7581 | biostudies-arrayexpress
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