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ProteomicsA programmed decline in ribosome levels governs human early neurodevelopment
How reductions in ribosome biogenesis can result in tissue- and developmental-specific defects remain a mystery. Here we describe allelic variants in the ribosome biogenesis factor AIRIM/C1orf109 that are primarily associated with neurodevelopmental disorders. Using human cerebral organoids in combi...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD063298 | Pride
Tmtpro 18plex Ribosome Mtor 
GenomicsGenome-wide maps of Lsd1 binding sites in escort cells/early follicle cells and cap cells/terminal filament cells
Loss of Lsd1 in Drosophila in specific cells of the Drosophila ovary results in increased BMP signaling outside the cap cell niche and an expanded germline stem cell (GSC) phenotype. To better characterize the function of Lsd1 in different cell populations within the ovary, we performed Chromatin im...
ORGANISM(S): Drosophila melanogaster 
2014-02-15 | E-GEOD-54376 | biostudies-arrayexpress
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