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MetabolomicsRA-MAP: mapping the molecular immunological landscape in early rheumatoid arthritis with vaccine controls

Rheumatoid arthritis (RA) is a chronic inflammatory disorder with poorly defined aetiology characterised by synovial inflammation with variable disease severity and drug responsiveness. To investigate the peripheral blood immune cell landscape of RA, we performed comprehensive clinical and molecu...

2021-06-16 | MTBLS1497 | MetaboLights
GenomicsEGAD00000000054
NCI-H209 is an immortal cell line derived from a bone marrow metastasis of a patient with small cell lung cancer, taken before chemotherapy. The specimen showed histologically typical small cells with classic neuroendocrine features. NCI-BL209 is an EBV-transformed B-cell line derived from the same ...
EGAD00000000054 | EGA
GenomicsA small cell lung cancer genome reports complex tobacco exposure signatures
Cancer is driven by mutation. Worldwide, tobacco smoking is the major lifestyle exposure that causes cancer, exerting carcinogenicity through 60 chemicals that bind and mutate DNA. Using massively parallel sequencing technology, we sequenced a small cell lung cancer cell line, NCI-H209, to explore t...
EGAS00000000051 | EGA
UnknownHealth outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial.
Not available
S-EPMC3656722 | biostudies-literature
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
GenomicsICGC Benchmark 1 (CLL) - samples
Raw fastq files from WGS sequencing of CLL and matching blood normal for the ICGC Techval Benchmark1 study. Sequence data was provided to multiple centers for independent analysis and comparison.
EGAD00001001858 | EGA
GenomicsICGC Benchmark 2 (Medulloblastoma) - samples
Raw fastq files for sequence data generated at 5 sequencing centers from a Medulloblastoma sample and matching blood normal control.
EGAD00001001859 | EGA
UnknownInsights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.
Not available
S-EPMC12120264 | biostudies-literature
UnknownPioglitazone after Ischemic Stroke or Transient Ischemic Attack.
Not available
S-EPMC4887756 | biostudies-literature
UnknownEffect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial.
Not available
S-EPMC9115619 | biostudies-literature
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