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TranscriptomicsDifferentially expressed genes in human hippocampus and Tera-1 cell line versus HepG2, A549, NT2/D1 and NGP127 cells.
We discovered a new tissue specific enhancer originated from the human spesific endogenous retrovirus (hsERV). This enhancer displayed its activity in hippocampus and Tera-1 cell line as opposed to HepG2, A549, NT2/D1 and NGP127 cells. The aim of this study was to find transcription factors responsi...
ORGANISM(S): Homo sapiens 
2013-01-26 | E-GEOD-43773 | biostudies-arrayexpress
UnknownGREM, a technique for genome-wide isolation and quantitative analysis of promoter active repeats.
Not available
S-EPMC3303178 | biostudies-literature
UnknownAt least 50% of human-specific HERV-K (HML-2) long terminal repeats serve in vivo as active promoters for host nonrepetitive DNA transcription.
Not available
S-EPMC1641792 | biostudies-literature
UnknownThe human genome contains many types of chimeric retrogenes generated through in vivo RNA recombination.
Not available
S-EPMC169886 | biostudies-literature
TranscriptomicsExperimental gene expression analysis of 12 cancer cell lines
The accurate choice of anti-cancer drugs is important problem of modern medicine. We developed a new method for the selection of targeted drugs based on detection of specific intracellular signaling and metabolic pathways in the bioinformatic system termed OncoFinder before the treatment. We obtaine...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-GEOD-65314 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression analysis of CMV infected human fibroblasts in two cultures
Analysis of microRNA expression patterns in cytomegalovirus infected human fibroblasts for two cultures with differing sensitivity to the virus Non-coding RNAs were cloned from total RNA extracts obtained from 2 human fibroblast lines with differing sensitivity to CMV infection. For each line 3 type...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75305 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of CMV infected human fibroblasts in two cultures with differing sensitivity to the virus
Analysis of gene expression patterns in cytomegalovirus infected human fibroblasts for two cultures with differing sensitivity to the virus Total RNA obtained from 2 human fibroblast lines with differing sensitivity to CMV infection. For each line 3 types of samples are compared: pre-experimantal no...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75366 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in cancerous and normal human bladder tissues
Analysis of differential gene expression in urothelium cancer cells compared to healthy bladder cells. The goal of researh was to discover any differences in signaling pathways regulation between cancer and normal cells and searching potential molecular markers for early cancer diagnostics. Total RN...
ORGANISM(S): Homo sapiens 
2013-11-20 | E-GEOD-52519 | biostudies-arrayexpress
TranscriptomicsTranscriptome analisys of bone marrow mononuclear cells derived from pediatric patients with acute myeloid leucosis
The aim of this research was to explore activation/deactivation of signaling pathways in mononuclear cells from pediatric patients with acute myeloid leucosis and acute lymphoid leucosis. Mononuclear cells were separated shortly after bone marrow samples collection. Cells were obtained by a density ...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-84574 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of mononuclear cells derived from bone marrow of pediatric patients with acute myeloid leucosis, acute lymphoid leucosis and from heathy donors peripheral blood
The aim of this research was to explore activation/deactivation of signaling pathways in mononuclear cells from pediatric patients with acute myeloid leucosis and acute lymphoid leucosis. Mononuclear cells were separated shortly after bone marrow or blood samples collection. Cells were obtained by a...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-84575 | biostudies-arrayexpress
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