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TranscriptomicsGene expression analyses of SMAD4 knockdown in pancreatic cell line
The transforming growth factor ? (TGF-?) signaling protein SMAD4 is lost in 60% of PDAC, and this has been associated with poorer prognosis. We expressed SMAD4 in human PDAC cell lines BxPC3, by selection of stable clones containing an inducible SMAD4 Tet-ON construct. After 24h of SMAD4 expression,...
ORGANISM(S): Homo sapiens 
2015-08-20 | E-GEOD-70940 | biostudies-arrayexpress
TranscriptomicsDDR1 knockdown in BXPC3 cell line
Examination of effect of stable DDR1 knockdown by shRNA on transcriptional profile in BXPC3 cell line to understand role of DDR1 in tumorigenesis. Transcriptional profiles of parental BXPC3 cell line was compared to BXPC3 cells stably transfected with non-target shRNA or DDR1 shRNA, N=3 for each con...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-39207 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of gemcitabine resistant pancreatic cancer cell line subclones derived from BxPC3
We generated gemcitabine resistant subclones from the human pancreatic cancer cell line BxPC3 using chronic low dose exposure to gemcitabine. Three gemcitabine resistant subclones (BxGR-80C, BxGR-120C and BxGR-360C) were sequenced in addition to BxPC3 cells.
ORGANISM(S): Homo sapiens 
2021-12-21 | E-MTAB-11186 | biostudies-arrayexpress
GenomicsEffect of ANO1 overexpression and/or oncogenic KRAS on gene expression of BxPC3 cells
Effect of ANO1 overexpression and/or oncogenic KRAS on gene expression of BxPC3 cells
PRJNA837427 | ENA
UnknownDifferential Sensitivity to MEK Inhibitors Highlights Distinct Entosis Mechanisms in BxPC3 and MCF7 Cells.
Not available
S-EPMC12524069 | biostudies-literature
GenomicsThe effect of WB436B or siRNA towards STAT3 on the whole-transcriptome analysis with total RNA sequencing (RNA-Seq) in BxPC3 cells
The effect of WB436B or siRNA towards STAT3 on the whole-transcriptome analysis with total RNA sequencing (RNA-Seq) in BxPC3 cells
PRJNA898805 | ENA
GenomicsmRNA-seq of gemcitabine resistant pancreatic cancer cell line subclones derived from BxPC3
mRNA-seq of gemcitabine resistant pancreatic cancer cell line subclones derived from BxPC3
PRJEB48965 | ENA
GenomicsmiRNA expression data from pancreatic ductal adenocarcinoma (PDAC) cell line BxPC3 and its cisplatin-resistant derivative BxPC3-R
Differential expression of miRNAs between parental and cisplatin-resistant PDAC cells was analyzed to elucidate the role of miRNAs in the acquired resistance of pancreatic cancer cells to cisplatin. Cisplatin-resistant BxPC3-R cells were developed from the parental BxPC3 cell line by culturing them ...
ORGANISM(S): synthetic construct Homo sapiens 
2016-05-01 | GSE79506 | GEO
TranscriptomicsEffect of ANO1 overexpression and/or oncogenic KRAS on gene expression of BxPC3 cells
RNA seq analysis was performed to assess the transcriptional profiles of BxPC3 cells with different status of ANO1 and KRAS.
ORGANISM(S): Homo sapiens 
2023-03-31 | GSE202825 | GEO
GenomicsSMARCA4 CUT&Tag profiling in parental and ARID1A-knockdown BxPC3 pancreatic cancer clones
SMARCA4 CUT&Tag profiling in parental and ARID1A-knockdown BxPC3 pancreatic cancer clones
PRJNA1533300 | ENA
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