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ProteomicsThe C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent potentially lethal monogenic disorder. Mutations in the PKD1 gene, which encodes polycystin-1 (PC1), account for approximately 78% of cases. PC1 is a large 462-kDa protein that undergoes cleavage in its N and C-terminal domai...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-17 | PXD040210 | Pride
Metabolism Polycystin-1 (pc1) C-terminal tail (ctt) Autosomal dominant polycystic kidney disease (adpkd) Nicotinamide nucleotide transhydrogenase (nnt) Mitochondria 
GenomicsModular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation
Modular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation
PRJNA527269 | ENA
TranscriptomicsModular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation
Stimulator of Interferon Genes (STING) is a key regulator of type I interferon and pro-inflammatory responses during infection, cellular stress, and cancer. Here we reveal a mechanism for how STING balances activation of IRF3- and NF-κB-dependent transcription, and discover that acquisition of discr...
ORGANISM(S): Mus musculus 
2019-06-10 | GSE128363 | GEO
UnknownC-terminal tail of human immunodeficiency virus gp41: functionally rich and structurally enigmatic.
Not available
S-EPMC3542723 | biostudies-literature
UnknownThe C-terminal tail of the bacterial translocation ATPase SecA modulates its activity.
Not available
S-EPMC6620043 | biostudies-literature
UnknownLigand-induced Ordering of the C-terminal Tail Primes STING for Phosphorylation by TBK1.
Not available
S-EPMC4972534 | biostudies-literature
UnknownRole of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae.
Not available
S-EPMC6344880 | biostudies-literature
UnknownDissecting the Functional Contributions of the Intrinsically Disordered C-terminal Tail of Bacillus subtilis FtsZ.
Not available
S-EPMC8922553 | biostudies-literature
UnknownProperties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes.
Not available
S-EPMC2934699 | biostudies-literature
UnknownIdentification of protein-protein and protein-ribosome interacting regions of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L.
Not available
S-EPMC2966113 | biostudies-literature
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