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MetabolomicsNPC1 regulates the distribution of phosphatidylinositol 4 kinases at Golgi and Lysosome membranes
Cholesterol and phosphoinositides (PI) are two critically important lipids that are found in cellular membranes and dysregulated in many disorders. Therefore, uncovering molecular pathways connecting these essential lipids may offer new therapeutic insights. We report that loss of function of lysoso...
2021-09-15 | MTBLS2612 | MetaboLights
TranscriptomicsMitochondrial beta-cyanoalanine synthase is essential for root hair formation in Arabidopsis thaliana
Cyanide is stoichiometrically produced as a co-product of the ethylene biosynthesis pathway, and it is detoxified by the b-cyanoalanine synthase enzyme. The molecular and phenotypical analysis of T-DNA insertional mutants of the mitochondrial b-cyanoalanine synthase CYS-C1 suggests that discrete acc...
ORGANISM(S): Arabidopsis thaliana 
2010-10-01 | E-GEOD-19242 | biostudies-arrayexpress
MetabolomicsSex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS RP POS assay)

Women have a lower incidence of colorectal cancer (CRC) than men, however, they have a higher incidence of right-sided colon cancer (RCC). This is of concern as patients with RCC have the poorest clinical outcomes among all CRC patients. Aberrant metabolism is a known hallmark and therapeutic tar...

2020-03-19 | MTBLS1129 | MetaboLights
MetabolomicsSex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS RP NEG assay)

Women have a lower incidence of colorectal cancer (CRC) than men, however, they have a higher incidence of right-sided colon cancer (RCC). This is of concern as patients with RCC have the poorest clinical outcomes among all CRC patients. Aberrant metabolism is a known hallmark and therapeutic tar...

2020-03-19 | MTBLS1130 | MetaboLights
MetabolomicsSex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS HILIC NEG assay)

Women have a lower incidence of colorectal cancer (CRC) than men, however, they have a higher incidence of right-sided colon cancer (RCC). This is of concern as patients with RCC have the poorest clinical outcomes among all CRC patients. Aberrant metabolism is a known hallmark and therapeutic tar...

2020-03-19 | MTBLS1124 | MetaboLights
MetabolomicsSex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype (UPLC-MS HILIC POS assay)

Women have a lower incidence of colorectal cancer (CRC) than men, however, they have a higher incidence of right-sided colon cancer (RCC). This is of concern as patients with RCC have the poorest clinical outcomes among all CRC patients. Aberrant metabolism is a known hallmark and therapeutic tar...

2020-03-19 | MTBLS1122 | MetaboLights
MetabolomicsLimosilactobacillus reuteri in Promoting Growth Performance and Regulating Lipid Metabolism in Zuili Black Pigs

Abstract

Background

The gut microbiota is a key regulator of host lipid metabolism. In indigenous pigs, variation in growth performance and intramuscular fat (IMF) deposition has been linked to microbiota-host interactions, yet the specific taxa and metabolites that govern host lipid ...

2025-09-20 | MTBLS13017 | MetaboLights
TranscriptomicsC1 metabolism in Corynebacterium glutamicum: an endogenous pathway for oxidation of methanol to carbon dioxide
Methanol is considered as an interesting carbon source in biobased microbial production processes. As Corynebacterium glutamicum is an important host in industrial biotechnology, in particular for amino acid production, we performed studies on the response of this organism to methanol. C. glutamicum...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-09-27 | E-GEOD-49936 | biostudies-arrayexpress
UnknownMetabolic role of pyrophosphate-linked phosphofructokinase pfk for C1 assimilation in Methylotuvimicrobium alcaliphilum 20Z.
Not available
S-EPMC7298851 | biostudies-literature
MetabolomicsSARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and autoimmune responses as observed in severe and long COVID-19 patients. Here we show that SARS-CoV-2 modulates cellular metabolism and reduces ...
2021-06-11 | MTBLS2840 | MetaboLights
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