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TranscriptomicsAffy Sjogren
Retuximab response transcription profiling in salivary glands from Sjogren patients
ORGANISM(S): Homo sapiens 
2010-01-05 | E-MEXP-1883 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of minor salivary glands to identify distinct patterns of gene expression in patients with primary Sj¸gren?s syndrome (pSS), a frequent and prototype systemic autoimmune disease
Analysis of targets organs might help to get new insights into the pathogenesis of autoimmune diseases. We used global gene expression profiling of minor salivary glands to identify distinct patterns of gene expression in patients with primary Sjögren’s syndrome (pSS), a frequent and prototype syste...
ORGANISM(S): Homo sapiens 
2005-10-01 | E-MEXP-419 | biostudies-arrayexpress
TranscriptomicscRel sang
NF-kB is a transcriptional factor that consists in homo and heterodimers of the large family of Rel subunits. Among the most important functions for NF-kB, initiation of immunological/inflammatory responses and regulation of cell proliferation/apoptosis which are the major features of severe infecti...
ORGANISM(S): Mus musculus 
2011-10-14 | E-MEXP-2944 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pancreas from patients suffering cancer (malignant tumors) and controls (benign tumors)
Comparison of expression profiling of pancreas from patients suffering cancer (malignant tumors) and controls (benign tumors).
ORGANISM(S): Homo sapiens 
2009-03-25 | E-MEXP-1914 | biostudies-arrayexpress
TranscriptomicsC.Nahmias_MDA231_Ang
Human breast cancer cells (MDA-MB-231) were cultured in serum-free conditions and either left untreated or treated for 24h in presence of 100nM Angiotensin II. Total RNA was extracted using trizol and reverse transcribed prior to analysis.
ORGANISM(S): Homo sapiens 
2012-12-05 | E-MEXP-3470 | biostudies-arrayexpress
TranscriptomicsINTERLEUKIN 15-DEPENDENT T CELL-LIKE INNATE INTRAEPITHELIAL LYMPHOCYTES DEVELOP IN THE INTESTINE AND TRANSFORM INTO LYMPHOMAS IN CELIAC DISEASE
The nature of gut intraepithelial lymphocytes lacking antigen receptors remains controversial. Herein we showed that, in humans and in mice, innate intestinal intraepithelial lymphocytes expressing intracellular CD3 (iCD3+ innate IELs) differentiate along an Id2 transcription factor (TF)-independent...
ORGANISM(S): Homo sapiens 
2016-11-23 | E-MTAB-4960 | biostudies-arrayexpress
TranscriptomicsKlhl6 deficiency impairs transitional B cell survival and differentiation
Klhl6 belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ domain and 4 to 6 Kelch motifs in tandem. Several of these proteins function as adaptors of the Cullin3 E3 ubiquitin ligase complex. Here we report that Klhl6 deficiency induces, as previously described, a two-fold re...
ORGANISM(S): Mus musculus 
2018-07-17 | E-MTAB-5928 | biostudies-arrayexpress
Transcriptomicskeyzer_Lonlay
Transcriptom profiling performed on myotubes derived from 3 patients carrying two recessively-inherited mutations in LPIN1 gene and 3 age and sex matched controls with or without TNF-alpha plus IL-1-beta stimulation for 24h.
ORGANISM(S): Homo sapiens 
2013-10-17 | E-MEXP-3761 | biostudies-arrayexpress
TranscriptomicsK.Woollard_Aglient
Human monocytes are phagocytic leucocytes which circulate in the peripheral blood and play important roles in immunity and inflammation. They also represent circulating M-^QmetabolicM-^R sentinels in plasma, uptake lipids following food intake, and contribute to atherosclerotic plaque formation. We ...
ORGANISM(S): Homo sapiens 
2012-09-19 | E-MEXP-3377 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cultured fibroblastic cell lines from Rett syndrome patients
Transcription profiling of cultured fibroblastic cell lines from Rett syndrome patients. Rett syndrome (symbolized RTT) is caused by mutations in the gene MECP2 located on the X chromosome. We compared cell lines mutated clones versus non mutated.
ORGANISM(S): Homo sapiens 
2009-12-19 | E-MEXP-1956 | biostudies-arrayexpress
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