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TranscriptomicsMesp1 induces a subset of hematopoietic-associated transcription factors in ES cell-derived Flk1+Tie2+ endothelium
Previously, we reported that the transcription factor Mesp1 promotes the cell fates of cardiomyocytes, smooth muscle, and vascular endothelium. Recently, hematopoietic stem cells (HSCs) were shown to derive from hemogenic endothelium. Since Mesp1 regulates development of endothelium, it potentially...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-34537 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse P5 cerebellum to investigate conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of neuroblastoma
Identification of common mechanisms underlying organ development and primary tumor formation should yield new insights into tumor biology and facilitate the generation of relevant cancer models. We have developed a novel method to project the gene expression profiles of medulloblastomas (MBs)—human ...
ORGANISM(S): Mus musculus 
2009-01-30 | E-GEOD-14514 | biostudies-arrayexpress
TranscriptomicsProtective unfolded protein response in human pancreatic beta cells transplanted into mice
Islet transplantation exposes beta cells to mild hyperglycemia and to the abnormal environment of the transplant site. These conditions may affect beta cells and induce the expression of genes involved in beta cell damage. Gene expression profile of human beta cells exposed to mild hyperglycemia by ...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-22097 | biostudies-arrayexpress
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