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TranscriptomicsRNA-seq comparison of Clostridium acetobutylicum wild-type and pks mutant under batch fermentation conditions.
The goal of this experiment is compare gene expression profiles between C. acetobutylicum wild-type and pks mutant strains to determine which genes might be under the control of self-produced polyketides. Samples for RNA-seq comparison were taken from batch fermentation cultures 26 hours post-inocul...
ORGANISM(S): Clostridium acetobutylicum 
2017-09-27 | E-MTAB-6019 | biostudies-arrayexpress
MetabolomicsBiosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in Actinobacteria
A putative lipopeptide biosynthetic gene cluster is conserved in many species of Actinobacteria, including Mycobacterium tuberculosis and Mycobacterium marinum, but the specific function of the encoding proteins has been elusive. Using both in vivo heterologous reconstitution and in vitro biochemica...
2017-07-18 | MTBLS454 | MetaboLights
TranscriptomicsA comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequence Quality Control consortium
We present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the United States Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference RNA samples with built-in controls, we ...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-56457 | biostudies-arrayexpress
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