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MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
MetabolomicsNorbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFkB, MAPK and STAT3 activation and blocking metabolic reprogramming

Inflammation is thought to be a key cause of many chronic diseases and cancer. However, current therapeutic agents to control inflammation have limited long-term use potential due to various side-effects. This study aimed to examine norbergenin, a constituent of traditional anti-inflammatory reci...

2023-04-06 | MTBLS7127 | MetaboLights
MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
UnknownA dietary pattern promoting gut sulfur metabolism is associated with increased mortality and altered circulating metabolites in low-income American adults.
Not available
S-EPMC12001102 | biostudies-literature
UnknownStable small quantum dots for synaptic receptor tracking on live neurons.
Not available
S-EPMC4240739 | biostudies-literature
TranscriptomicsGene expression analysis of primary human myeloid precursor cells treated with O6-benzylguanine (6BG) and Temozolomide (TMZ)
For the comparison of 6BG/TMZ with control sample, the predominant annotation among the upregulated genes is M-bM-^@M-^XapoptosisM-bM-^@M-^Y. The majority of the downregulated genes is assigned to heat shock proteins and proteins which bind unfolded proteins. To look at early changes in gene express...
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-44122 | biostudies-arrayexpress
UnknownA GICA-TVGL framework to study sex differences in resting state fMRI dynamic connectivity.
Not available
S-EPMC10187053 | biostudies-literature
UnknownA Sputtered Silicon Oxide Electrolyte for High-Performance Thin-Film Transistors.
Not available
S-EPMC5429786 | biostudies-literature
UnknownActivation of Cannabinoid Receptor 2 Prevents Colitis-Associated Colon Cancer through Myeloid Cell De-activation Upstream of IL-22 Production.
Not available
S-EPMC7501437 | biostudies-literature
UnknownRefined measure of functional connectomes for improved identifiability and prediction.
Not available
S-EPMC6865523 | biostudies-literature
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