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TranscriptomicsTH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow. Advances in therapy and understanding of the metastatic process have been lim...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42548 | biostudies-arrayexpress
TranscriptomicsTH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow. Advances in therapy and understanding of the metastatic process have been lim...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42254 | biostudies-arrayexpress
UnknownQualitative analysis of the Meals, Mindfulness, & Moving Forward (M3 ) lifestyle programme: Cultivating a 'safe space' to start on a 'new path' for youth with early episode psychosis.
Not available
S-EPMC10952130 | biostudies-literature
UnknownCollagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis.
Not available
S-EPMC7541088 | biostudies-literature
UnknownMethotrexate Inhibits T Cell Proliferation but Not Inflammatory Cytokine Expression to Modulate Immunity in People Living With HIV.
Not available
S-EPMC9374564 | biostudies-literature
UnknownImpaired complement regulation drives chronic lung allograft dysfunction after lung transplantation.
Not available
S-EPMC12721912 | biostudies-literature
TranscriptomicsIn vivo electroporation-based conditional oncogenic activation implicates multiple distinct cellular origins for Group3 medulloblastoma
We examined the transformation susceptibility of different cerebellar stem/progenitors by developing several new Group3 medulloblastoma murine models using orthotopic transplantation and in utero electroporation (EP)-based in vivo gene transfer with Cre/LoxP-mediated conditional Myc gene activation ...
ORGANISM(S): Mus musculus 
2015-02-13 | E-GEOD-65888 | biostudies-arrayexpress
TranscriptomicsPreclinical Models for Neuroblastoma: Establishing a Baseline for Treatment
Here we characterize and optimize both systems to increase their utility for preclinical studies. We show that TH-MYCN mice develop tumors in the paraspinal ganglia, but not in the adrenal, with cellular and gene expression patterns similar to human NB. In addition, we present a new ultrasound guide...
ORGANISM(S): Mus musculus 
2011-03-17 | E-GEOD-27516 | biostudies-arrayexpress
UnknownHigh-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19.
Not available
S-EPMC12306582 | biostudies-literature
UnknownPolygenic and developmental profiles of autism differ by age at diagnosis.
Not available
S-EPMC12571882 | biostudies-literature
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