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TranscriptomicsA familial disorder of altered DNA-methylation
In a subset of imprinting disorders caused by epimutations, multiple imprinted loci are affected. We have investigated the clinical and molecular features of a familial DNA methylation disorder. Bisulphite converted DNA from the 60 samples were hybridised to the Illumina Infinium 27k Human Methylati...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-47879 | biostudies-arrayexpress
TranscriptomicsArray-based DNA methylation profiling in male infertility reveals allele-specific DNA methylation in PIWIL1 and PIWIL2
Array-based DNA methylation profiling in peripheral blood leukocytes of 30 infertile men with impaired spermatogenesis as compared to 10 fertile men using the Illumina Infinium HumanMethylation 450k Bead Chip reveald 471 CpG sites (287 genes) to be differentially methylated between both groups. Thes...
ORGANISM(S): Homo sapiens 
2014-02-16 | E-GEOD-51245 | biostudies-arrayexpress
TranscriptomicsIn vivo investigations of the effect of short- and long-term recombinant growth hormone treatment on DNA-methylation in humans
Treatment with recombinant human growth hormone (rhGH) has been consistently reported to induce transcriptional changes in various human tissues including peripheral blood. For other hormones it has been shown that the induction of such transcriptional effects is conferred or at least accompanied by...
ORGANISM(S): Homo sapiens 
2015-01-23 | E-GEOD-57204 | biostudies-arrayexpress
TranscriptomicsIn vivo investigations of the effect of short- and long-term recombinant growth hormone treatment on DNA-methylation in humans
Treatment with recombinant human growth hormone (rhGH) has been consistently reported to induce transcriptional changes in various human tissues including peripheral blood. For other hormones it has been shown that the induction of such transcriptional effects is conferred or at least accompanied by...
ORGANISM(S): Homo sapiens 
2015-01-23 | E-GEOD-57107 | biostudies-arrayexpress
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