The purpose of the experiment was to generate a time course of gene expression following irradiation. The goal was then to model this data to extract hidden variables - chiefly, the activity profiles of the p53 transcription factor. Using this information the aim was to predict which transcripts cha...
This a model from the article:
Understanding the slow depletion of memory CD4+ T cells in HIV infection.
Yates A, Stark J, Klein N, Antia R, Callard R. PLoS Med.
2007;4(5):e177. 17518516
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Abstract:
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