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TranscriptomicsTranscription signature of Multiple Sclerosis
This SuperSeries is composed of the following subset Series: GSE17393: Transcription signature of Multiple Sclerosis in peripheral blood mononuclear cells. GSE17409: Pregnancy changes expression in peripheral blood mononuclear cells of healthy donors GSE17410: Pregnancy changes expression in periphe...
ORGANISM(S): Homo sapiens 
2010-01-10 | E-GEOD-17449 | biostudies-arrayexpress
GenomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51926 | biostudies-arrayexpress
TranscriptomicsTranscription signature of Multiple Sclerosis in peripheral blood mononuclear cells.
Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood. This data series contains the subset of data used to generate a MS signature comparing female...
ORGANISM(S): Homo sapiens 
2010-01-10 | E-GEOD-17393 | biostudies-arrayexpress
TranscriptomicsEffects of bisphenol A on gene expression in adipocytes from lean children: association to metabolic disorders
Bisphenol A (BPA) is a xenobiotic endocrine disrupting chemical. In vitro and in vivo studies indicated that BPA alters endocrine-metabolic pathways in adipose tissue increasing the risk of developing metabolic disorders. BPA effects on human adipocytes, specifically in children, are poorly investig...
ORGANISM(S): Homo sapiens 
2015-07-09 | E-GEOD-58516 | biostudies-arrayexpress
TranscriptomicsPregnancy changes expression in peripheral blood mononuclear cells of healthy donors
Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood. This data series contains the subset of data used to generate a healthy donors signature comp...
ORGANISM(S): Homo sapiens 
2010-01-09 | E-GEOD-17409 | biostudies-arrayexpress
TranscriptomicsPregnancy changes expression in peripheral blood mononuclear cells of Multiple Sclerosis (MS) patients
Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood. This data series contains the subset of data used to generate a MS signature comparing female...
ORGANISM(S): Homo sapiens 
2010-01-10 | E-GEOD-17410 | biostudies-arrayexpress
TranscriptomicsApoptosis induced by Piroxicam/Cisplatin combined treatment is triggered by p21 in mesothelioma
Here we report that piroxicam/cisplatin combined treatment exerts an apoptotic effect on mesothelioma cells. Genome-wide transcriptome analyses lead us to identify p21 as the possible apoptosis mediator acting as downstream target of the piroxicam/cisplatin treatment. To analyze the potential therap...
ORGANISM(S): Homo sapiens 
2011-11-20 | E-GEOD-22445 | biostudies-arrayexpress
GenomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells (ChIP-seq)
PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this s...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51816 | biostudies-arrayexpress
TranscriptomicsEndometriosis transcription profiling
Endometriosis is a complex pathological condition in which multiple components are involved in the disease development and clinical outcome. Endometriosis is mainly an inflammatory codition estrogen-dependent, with unknown pathogenesis, that is characterized by dissemination of edometrium tissue in ...
ORGANISM(S): Homo sapiens 
2013-11-30 | E-GEOD-25628 | biostudies-arrayexpress
TranscriptomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells (RNA-seq)
PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this s...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51553 | biostudies-arrayexpress
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