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TranscriptomicsA strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice
Tmprss6 is the master inhibitor of hepcidin and its inactivation causes iron refractory iron deficiency anemia both in human and in mice. Mice with iron deficiency anemia (IDA)-low hepcidin show a pro-inflammatory response that is blunted in iron deficienct-high hepcidin Tmprss6 null mice. We invest...
ORGANISM(S): Mus musculus 
2013-10-09 | E-GEOD-46287 | biostudies-arrayexpress
TranscriptomicsRNAseq of the spleen of Hbb(th3/+) mice transplanted with bone marrow from Tfr2-ko or Tfr2 wt mice
C57Bl/6 Ly5.1 male mice lethally irradiated have been transplanted at 8 weeks of age with bone marrow from Hbb(th3/+)/Tfr2(+/+) or Hbb(th3/+)/Tfr2(-/-) mice (Bone marrow in a mixed genetic background C57BL6/129Sv). After transplantation, the mice have been maintained in a standard diet for 22 weeks ...
ORGANISM(S): Mus musculus 
2020-03-04 | E-MTAB-6606 | biostudies-arrayexpress
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