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TranscriptomicsTranscription profiling of human MDAMB231 breast cancer cells by Parvin-beta in 2D vs 3D culture conditions
Parvin-beta is a focal adhesion protein downregulated in human breast cancer cells. Loss of Parvin-beta contributes to increased integrin-linked kinase activity, cell-matrix adhesion, and invasion through the extracellular matrix in vitro. The effect of ectopic Parvin-beta expression on the transc...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9747 | biostudies-arrayexpress
TranscriptomicsAlteration of microRNA gene expression by EBV encoded LMP1 oncogene
The Epstein Barr virus (EBV) encoded latent membrane protein-1 (LMP1) is a functional homologue of the tumor necrosis factor receptor family and contributes substantially to the oncogenic potential of EBV through activation of Nuclear Factor-kappaB (NF-kappaB). MicroRNAs (miRNAs) are a class of smal...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10105 | biostudies-arrayexpress
TranscriptomicsThe EBV latent membrane protein 1 (LMP1) induces cellular microRNA-146a, a modulator of lymphocyte signaling pathways
This SuperSeries is composed of the following subset Series: GSE10057: The Epstein-Barr Virus latent membrane protein 1 (LMP1) induces cellular microRNA146a GSE10105: Alteration of microRNA gene expression by EBV encoded LMP1 oncogene Keywords: SuperSeries Refer to individual Series
ORGANISM(S): Homo sapiens 
2008-01-08 | E-GEOD-10107 | biostudies-arrayexpress
UnknownTopical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing.
Not available
S-EPMC5976625 | biostudies-literature
TranscriptomicsThe Epstein-Barr Virus latent membrane protein 1 (LMP1) induces cellular microRNA146a
The Epstein Barr virus (EBV) encoded latent membrane protein-1 (LMP1) is a functional homologue of the tumor necrosis factor receptor family and contributes substantially to the oncogenic potential of EBV through activation of Nuclear Factor-kappaB (NF-kappaB). MicroRNAs (miRNAs) are a class of smal...
ORGANISM(S): Homo sapiens 
2008-01-03 | E-GEOD-10057 | biostudies-arrayexpress
TranscriptomicsDynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
Tamoxifen is the most widely prescribed anti-estrogen treatment for patients with ER-positive breast cancer. However, there is still a need for biomarkers that reliably predict endocrine sensitivity in breast cancers and these may well be expressed in a dynamic manner. In this study we assessed ge...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-22386 | biostudies-arrayexpress
TranscriptomicsRunx1 and Runx2 act in concert to suppress Wnt/b-catenin-driven mammary tumourigenesis impacting on mammary stemness and the immune microenvironment
The genes for transcription factor RUNX1 and its binding partner CBFb have been reported to be mutated in human breast cancer. We show for the first time that loss of Runx1 in a genetically engineered mouse model results in accelerated disease onset and tumour development aligning RUNX1 as a tumour ...
ORGANISM(S): Mus musculus 
2026-05-01 | E-MTAB-15078 | biostudies-arrayexpress
UnknownExome Sequencing and the Management of Neurometabolic Disorders.
Not available
S-EPMC4983272 | biostudies-literature
UnknownMachine learning-based spatial characterization of tumor-immune microenvironment in the EORTC 10994/BIG 1-00 early breast cancer trial.
Not available
S-EPMC11889191 | biostudies-literature
UnknownMolecular and biogeochemical evidence for methane cycling beneath the western margin of the Greenland Ice Sheet.
Not available
S-EPMC4992074 | biostudies-literature
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