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MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
TranscriptomicsTranscription profiling by array of adult zebrafish control and post-lesion retina to investigate the molecular determinants of retinal regeneration in adult vertebrate
Purpose: Investigate the molecular determinants of retinal regeneration in adult vertebrates by analyzing the gene expression profiles of control and post-lesion retina of adult zebrafish, a system that regenerates following injury. Methods: Gene expression profiles of zebrafish retina and brain wer...
ORGANISM(S): Danio rerio 
2005-09-16 | E-GEOD-3303 | biostudies-arrayexpress
TranscriptomicsThe role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells
BACKGROUND: Combination antiretroviral therapy (cART) is able to control HIV-1 viral replication, however long-lived latent infection in resting memory CD4+ T-cells persist. The mechanisms for establishment and maintenance of latent infection in resting memory CD4+ T-cells remain unclear. Previously...
ORGANISM(S): Homo sapiens 
2015-12-23 | E-GEOD-70106 | biostudies-arrayexpress
TranscriptomicsDynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
Tamoxifen is the most widely prescribed anti-estrogen treatment for patients with ER-positive breast cancer. However, there is still a need for biomarkers that reliably predict endocrine sensitivity in breast cancers and these may well be expressed in a dynamic manner. In this study we assessed ge...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-22386 | biostudies-arrayexpress
MetabolomicsDirect on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth

The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct on-swab metabolic profiling by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) for sample preparation-free characterisation of...

2021-09-23 | MTBLS717 | MetaboLights
TranscriptomicsDC populations incubated with rAd5, rAd28, rAd35, TLR7/8-ligand, or unexposed
Recombinant adenovirus vectors (rAds) are being investigated as vaccine delivery vehicles in pre-clinical and clinical studies. rAds constructed from different serotypes differ in receptor usage, tropism, and ability to activate cells, aspects of which likely contribute to their different immunogeni...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-37128 | biostudies-arrayexpress
UnknownDirect on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth.
Not available
S-EPMC8514602 | biostudies-literature
UnknownEfficacy and Safety of Remdesivir in People With Impaired Kidney Function Hospitalized for COVID-19 Pneumonia: A Randomized Clinical Trial.
Not available
S-EPMC11581693 | biostudies-literature
UnknownCommon schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Not available
S-EPMC5918692 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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