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TranscriptomicsRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Recently, we defined four subtypes of pancreatic cancer that are associated with distinct histopathological characteristics and differential survival, namely, Squamous, Pancreatic Progenitor, Immunogenic, and ADEX (Bailey et al 2016, Nature). We also found that loss of CXCR2 was associated with a sw...
ORGANISM(S): Mus musculus 
2018-05-01 | E-MTAB-6620 | biostudies-arrayexpress
Transcriptomicssingle cell RNAseq of memory B cells in the context of rituximab-treated ITP patients
Rituximab (RTX) is widely used as a first-line therapeutic strategy in B cell-mediated autoimmune diseases. However, a large proportion of patients either do not respond to the treatment or relapse during B cell reconstitution. Primary immune thrombocytopenia (ITP) is a prototypic B cell mediated au...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9955 | biostudies-arrayexpress
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
UnknownGenetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Not available
S-EPMC3431328 | biostudies-literature
UnknownIntegrative analysis of 111 reference human epigenomes.
Not available
S-EPMC4530010 | biostudies-literature
UnknownComprehensive molecular characterization of mitochondrial genomes in human cancers.
Not available
S-EPMC7058535 | biostudies-literature
UnknownWorld health Organization's guidance for tracking non-communicable diseases towards sustainable development goals 3.4: an initiative for facility-based monitoring.
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S-EPMC12269858 | biostudies-literature
UnknownPhenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Not available
S-EPMC6820948 | biostudies-literature
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
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S-EPMC10600726 | biostudies-literature
UnknownAdult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study.
Not available
S-EPMC5644573 | biostudies-literature
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