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TranscriptomicsSerial gene expression profiling in the liver of Pdgf-c Tg mice that developed hepatic fibrosis and tumors
Over expression of PDGF-C in mouse liver resulted in the progression of hepatic fibrosis, steatosis and the development of HCC; this mouse model closely resembles the human HCC that is frequently associated with hepatic fibrosis. Peretinoin (generic name; code, NIK-333), developed by the Kowa Compan...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-31431 | biostudies-arrayexpress
TranscriptomicsInduction of hepatocellular carcinoma through activation of stromal cells in Pdgf-c transgenic mice
Liver cirrhosis is a strong risk factor for the development of hepatocellular carcinoma (HCC), yet the mechanisms by which cirrhosis predisposes patients to tumorigenesis are not well understood. Transgenic mice expressing platelet-derived growth factor C (Pdgf-c) under the control of the albumin pr...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-38199 | biostudies-arrayexpress
GenomicsInternational Genetics of Parkinson Disease Progression (IGPP) Consortium GWAS Summary Results
To characterize how genetic variation influences the progression of Parkinson’s disease to dementia, which is a major determinant for quality of life, we performed a longitudinal genome-wide survival study (GWSS). Risk profile analysis was performed with a novel polygenic hazard score in longit...
EGAS00001005110 | EGA
Genomics8f81ce09-cd65-468c-a27a-d4f4863b24c4 - samples
The data are the aggregate results from an IGPP Consortium genome-wide survival study, showing overall risk for Parkinson disease progression associated with each variant in a longitudinal cohort study. 11.2 million deeply imputed variants in 3,821 PD patients who were prospectively tracked with 36,...
EGAD00001007060 | EGA
GenomicsInternational Genetics of Parkinson Disease Progression (IGPP) Consortium GWSS Summary Results Data Access Committee
Data Access Committee EGAC00001002012
EGAC00001002012 | EGA
UnknownInteractions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies.
Not available
S-EPMC2992213 | biostudies-literature
UnknownSimvastatin in Critically Ill Patients with Covid-19.
Not available
S-EPMC10755839 | biostudies-literature
UnknownMeta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group.
Not available
S-EPMC8386522 | biostudies-literature
UnknownSame data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology.
Not available
S-EPMC11804095 | biostudies-literature
UnknownCharacterizing Long COVID in Children and Adolescents.
Not available
S-EPMC11339705 | biostudies-literature
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