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TranscriptomicsTranscription profiling by array of human DA-MB-231 breast cancer cells treated with various SCFA-hexosamine analogs
The purpose of this study was to characterize the gene expression profile of MDA-MB-231 breast cancer cells treated with various SCFA-hexosamine analogs to better understand the role of various modifications to this scaffold. Experiment Overall Design: In total, six analogs were investigated in this...
ORGANISM(S): Homo sapiens 
2009-05-17 | E-GEOD-11407 | biostudies-arrayexpress
TranscriptomicsMycobacterial cells have dual nickel-cobalt sensors: sequence-relationships and metal-sites of metal-responsive repressors are not congruent.
A novel ArsR-SmtB family transcriptional repressor, KmtR, has been characterised from mycobacteria. Mutants of M. tuberculosis lacking kmtR show elevated expression of Rv2025c encoding a deduced CDF-family metal-exporter. KmtR-dependent repression of the cdf and kmtR operator-promoters was alleviate...
ORGANISM(S): Mycobacterium tuberculosis 
2007-09-17 | E-BUGS-49 | biostudies-arrayexpress
TranscriptomicsD4Z4-located miRNA
We have used a tiled microarray based on the D4Z4 sequence, and hybridized amplified transcripts from facioscapulohumeral muscular dystrophy (FSHD) and control (CTRL) samples to detect D4Z4 related expression. Microarrays were analyzed by GenePix Pro 6 (Axon). Local background corrected, median spot...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-12159 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of blood cells from hypertriglyceridemic men treated with docosahexaenoic acid shows suppression of LDLR and OLR1 gene expression.
Previously published results from our double-blind, placebo-controlled parallel study with docosahexaenoic acid (DHA) supplementation (3 g/d, 90 d) to hypertriglyceridemic men (39-66yr) showed that DHA reduced several risk factors for cardiovascular disease (CVD), including the plasma concentration ...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-20114 | biostudies-arrayexpress
TranscriptomicsRNA seq of rectal tumour tissue and paired healthy tissue, with EpCAM purification
Tumour tissue was immediately obtained post-surgery along with paired healthy tissue near (<2cm from tumour margin) and far (>10cm) from the tumour site. Each tissue was dissociated and stained with flow cytometry antibodies and sorted by FACS into Live/Dead-negative EpCAM-positive CD3-negative popu...
ORGANISM(S): Homo sapiens 
2020-02-27 | E-MTAB-8803 | biostudies-arrayexpress
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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