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UnknownRacial and Ethnic Variations in Lung Cancer Incidence and Mortality: Results From the Women's Health Initiative.
Not available
S-EPMC4872034 | biostudies-literature
ProteomicsBeta-cell Galphas signaling is critical for physiological and pharmacological enhancement of insulin secretion
Islet lysates were adjusted to 5 percent SDS in TEAB, pH 8.5, reduced and alkylated and digested with modified trypsin (Worthington) using an S-trap mini device (Protifi). Peptides were labeled with TMT16 reagents (lot ZH350094). Phosphopeptide enrichment used GL Sciences p10 TiO tips. LC-MS/MS used...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-05-13 | MSV000097882 | MassIVE
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
ProteomicsLate-life restoration of mitochondrial function reverses cardiac dysfunction in old mice
Redox proteomic data from the heart of young mice, old mice, or mice treated with SS31. Quantification of protein-S-glutathionylation was performed using an established redox proteomics workflow. LC-MS/MS raw data were searched with MS-GF+ against the mouse protein sequence database from the Uniprot...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-04-23 | MSV000085329 | MassIVE
ProteomicsA tissue-based draft map of the murine MHC class I immunopeptidome
The array of peptides presented to CD8+ T cells by major histocompatibility complex (MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the MHC class I immunopeptidome is ubiquitous in mammals and represents a critical component of the adaptive immune system, very lit...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-19 | MSV000084980 | MassIVE
ProteomicsUnusual cardiac myosin heavy chain post-translational modifications with systolic heart failure
In the present study, we aimed at defining whether cardiac myosin heavy chain (MYH7) post-translational modifications would be altered in systolic heart failure. For that, we had access to septal tissue from donors and from patients with non-genetic dilated cardiomyopathy or with ischemic cardiomyop...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD076695 | Pride
Heart failure  systolic dysfunction  myh7  myosin 
ProteomicsA time-resolved proteomic and prognostic map of COVID-19
We performed quantitative proteomic profiling of 786 plasma samples from COVID-19 inpatients, treated at two different hospitals (Charité – Universitätsmedizin Berlin and University Hospital of Innsbruck). Sampling was performed at multiple time points throughout the course of the disease, to create...
ORGANISM(S): Homo sapiens (Human) 
2021-07-19 | PXD025752 | Pride
Covid-19 Plasma Sars-cov2 Scanningswath 
TranscriptomicsLaternula elliptica siphon hypoxia treatment
The siphon taken from old and young Laternula elliptica, both control and subjected to hypoxic conditions, were compared.
ORGANISM(S): Laternula elliptica 
2014-02-20 | E-MEXP-3613 | biostudies-arrayexpress
TranscriptomicsLaternula elliptica gill hypoxia treatment
Two groups of Laternula elliptica, old and young, were subjected to both ambient control and hypoxic conditions, and their gills were extracted and hybridized on an array.
ORGANISM(S): Laternula elliptica 
2013-04-01 | E-MEXP-3611 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Laternula elliptica under heat stress
Microarray analysis of gene expression in the Antarctic clam Laternula elliptica after exposure to elevated temperatures
ORGANISM(S): Laternula elliptica 
2010-08-03 | E-MEXP-2336 | biostudies-arrayexpress
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