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ProteomicsA BioID-derived proximity interactome for SARS-CoV-2 proteins
The novel coronavirus SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic and has caused a major health and economic burden worldwide. Understanding how SARS-CoV-2 viral proteins behave in host cells can reveal underlying mechanisms of pathogenesis and assist in development of antiviral ther...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-18 | MSV000088245 | MassIVE
ProteomicsLoss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis
Here we utilized a mouse model of PDAC and human pancreatic cancer cell lines to investigate the role of HIF1alpha in pancreatic cancer. Contrary to the conventional notion that HIF1alpha plays a tumor promoting role in several cancers, our findings indicate a tumor suppressive role of HIF1alpha in ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-08-21 | MSV000084223 | MassIVE
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