Cancer immunology

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Unknown (49214)
Genomics (1315)
Proteomics (257)
Transcriptomics (89)
Models (15)
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Other (7)
Genomic (6)
Clinical (2)

Organisms

Allexis (229)
Arabidopsis thaliana (229)
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Methylohalobius crimeensis 10Ki (229)
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Physcomitrium patens (229)
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Pseudomonas putida KT2440 (229)
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Schizosaccharomyces pombe (229)
Schizosaccharomyces pombe 972h- (229)
Sinorhizobium meliloti BL225C (229)
Homo sapiens (70)
Mus musculus (55)
Canis lupus familiaris (2)
Schistosoma japonicum (1)
Gallus gallus (1)

Organisms

Mus musculus (586)
Homo sapiens (547)
Canis lupus familiaris (4)
Cricetulus griseus (3)
Mus (3)
Gallus gallus (3)
Salmonella enterica subsp. enterica serovar Typhimurium (2)
Candida albicans (2)
Rattus norvegicus (2)
synthetic construct (2)
Leucoraja erinaceus (1)
Escherichia coli O157:H7 str. EDL933 (1)
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Opisthorchis viverrini (1)
Acanthamoeba castellanii (1)
Oryctolagus cuniculus (1)
Neisseria gonorrhoeae (1)
Mycolicibacterium smegmatis (1)
Drosophila melanogaster (1)
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Escherichia coli (1)
Saccharomyces cerevisiae (1)

Repository

ENA (1305)
pride (229)
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geo (44)
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jPOST (1)

Tissue

Cell culture (63)
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T cell (22)
Blood (19)
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Disease

Colon cancer (21)
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Disease free (5)
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Acute leukemia (3)
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Cancer (3)
Lung adenocarcinoma (3)
Lung cancer (3)
Lymphoma (3)
Ovarian carcinoma (3)
B-cell acute lymphoblastic leukemia (2)
COVID-19 (2)
Fibrosarcoma (2)
Human immunodeficiency virus infectious disease (2)
Multiple myeloma (2)
Non-small cell lung carcinoma (2)
Pancreatic ductal adenocarcinoma (2)
Chicken Anaemia Virus infected (1)
Carcinoma (1)
Colorectal Neoplasms (1)
Not Available (1)
Atypical teratoid rhabdoid tumor (1)
B-lymphoblastic leukemia/lymphoma (1)
Bone giant cell tumor (1)

Technology Type

Mass Spectrometry (229)
Shotgun proteomics (119)
Affinity purification coupled with mass spectrometry proteomics (46)
Bottom-up proteomics (33)
Data-dependent acquisition (22)
Data-independent acquisition (13)
Mass spectrometry (9)
Gel-based experiment (8)
SRM/MRM (8)
Immunopeptidomics (6)
Top-down proteomics (6)
Chemical cross-linking coupled with mass spectrometry proteomics (3)
All-ion fragmentation (2)
DiaPASEF (2)
HDMSE (2)
Mass spectrometry imaging (2)
SWATH MS (2)
Affinity proteomics (1)
Glycoproteomics (1)
MSE (1)

Instrument Platform

Orbitrap Fusion Lumos (5)
Illumina NovaSeq 6000 (3)
Liquid Chromatography MS - positive - reverse phase (3)
Liquid Chromatography MS - negative - reverse phase (3)
Illumina MiSeq (2)
Q Exactive HF (2)
Liquid Chromatography MS - alternating - hilic (2)
Liquid Chromatography MS - positive - hilic (2)
ScanArray 5000 [PerkinElmer] (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Instrument (1)
6546 Q-TOF LC/MS (Agilent Instrument model) (1)
Impact (1)
LTQ Orbitrap (1)
Orbitrap Exploris 480 (1)
Orbitrap Fusion (1)
TimsTOF Pro (1)
TimsTOF Ultra (1)
TripleTOF 5600 (1)
MS Imaging - (1)
Liquid Chromatography MS - negative - hilic (1)
Not available (1)

Publication Date

2025 (59)
2024 (43)
2022 (39)
2021 (36)
2023 (35)
2026 (34)
2020 (32)
2018 (19)
2019 (14)
2013 (13)
2016 (11)
2015 (9)
2014 (9)
2005 (6)
2017 (5)
2012 (4)
2011 (4)
2010 (4)
2009 (4)
2007 (2)

UNIPROT ID/AC

Q9NSE2 (1)
P29350 (1)
P01588 (1)
P19235 (1)
P25445 (1)
P48023 (1)
O14543 (1)
O60674 (1)
P42229 (1)

CHEBI ID

CHEBI:29016 (3)
CHEBI:17368 (3)
CHEBI:28315 (2)
CHEBI:16264 (2)
CHEBI:17858 (2)
CHEBI:16856 (2)
CHEBI:18237 (2)
CHEBI:17126 (2)
CHEBI:22660 (2)
CHEBI:18186 (2)
CHEBI:16811 (2)
CHEBI:17234 (2)
CHEBI:28300 (2)
CHEBI:16708 (2)
CHEBI:28867 (2)
CHEBI:17562 (2)
CHEBI:25017 (2)
CHEBI:6650 (2)
CHEBI:28044 (2)
CHEBI:17015 (2)
CHEBI:16235 (2)
CHEBI:17750 (2)
CHEBI:73024 (2)
CHEBI:17084 (2)
CHEBI:16704 (2)
CHEBI:15318 (2)
CHEBI:16737 (2)
CHEBI:16919 (2)
CHEBI:59132 (1)
CHEBI:17089 (1)

Metabolite Name

Adenine (3)
Xanthine (3)
Uridine (3)
Creatinine (3)
Pyrrole-2-carboxylic acid (2)
Leucine (2)
Uracil (2)
Citrulline (2)
L-Threonine (2)
Palmitoleic acid (2)
L-Histidine (2)
Methionine (2)
Taurine (2)
Ascorbic acid (2)
Arginine (2)
Oxypurinol (2)
Tyrosine (2)
Guanine (2)
Phenylalanine (2)
Oleic acid (2)
Linoleic acid (2)
Myristic acid (2)
Cytidine (2)
Trehalose (2)
Creatine (2)
Tryptophan (2)
Inosine (2)
Hypoxanthine (2)
SuccinylGSH (1)
SuccinylCys (1)

First Public Date

2025 (161)
2023 (161)
2024 (150)
2026 (137)
2022 (127)
2021 (101)
2020 (101)
2014 (101)
2019 (84)
2015 (49)
2018 (46)
2017 (46)
2016 (28)
2013 (13)

Modelling Approach

Ordinary differential equation model (11)
Constraint-based model (1)

Study status

Not provided (1)
Completed (1)

Lab affiliation

Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (24)
National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (4)
Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany (3)
Institute for Research in Immunology and Cancer (IRIC) Université de Montréal, Department of Chemistry, Université de Montréal, MIL campus, Montréal, H2V 0B3, Canada (3)
University of Tübingen Interfaculty Institute for Cell Biology Department of Immunology Auf der Morgenstelle 15 72076 Tuebingen Germany (3)
1. Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. 2. Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. 3. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA (2)
1. Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Republic of Singapore 2. Department of Pharmacy, National University of Singapore 3. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CH Utrecht, the Netherlands (2)
Department of Cellular Immunology, German Cancer Research Center Heidelberg, Germany (2)
Department of Immunology and Cell Biology, Sherbrooke, QC, Canada (2)
Department of Immunology, Interfaculty Institute for Cell Biology, Eberhard Karls University Tübingen (2)
Department of Immunology, Interfaculty Institute for Cell Biology, Tübingen, Germany (2)
Department of Immunology, Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany (2)
Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (2)
Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Tübingen, Germany (2)
Departments of Immunology and Radiation Oncology Moffitt Cancer Center Tampa, FL, USA (2)
Dept. of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway (2)
Head, Dept of Immunology, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Ullernchausséen 70, 0379 Oslo, Norway (2)
Immunology Research Center, National Health Research Institutes, Zhunan, Taiwan. (2)
Immunology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA (2)
Institute for Research in Immunology and Cancer (IRIC), University of Montreal (2)
Institute for Research in Immunology and Cancer, Department of Chemistry, Université de Montréal, Montréal, Québec, Canada H3T 1J4 (2)
The Concern Foundation Laboratories at The Lautenberg Center for Immunology and Cancer Research IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel (2)
Tranlational Oncology Group, Center for Tumor Biology and Immunology, Philipps University, Marburg, Germany (2)
1 Department of Immunology, Interfaculty Institute for Cell Biology, Tübingen, Germany 2 German Cancer Consortium (DKTK), DKFZ Partner Site Tübingen, Tübingen, Germany (1)
1 Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Canada 2 Department of Chemistry, Université de Montréal, Montréal, Canada (1)
1 Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec, Canada. 2 Department of Chemistry, Université de Montréal, Montréal, Québec, Canada. 3 Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec, Canada. (1)
1. Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Germany 2. Cluster of Excellence iFIT (EXC2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, Germany 3. Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Germany 4. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), partner site Tübingen, Germany (1)
1. Gene Regulation, Stem Cells and Development group, PTS, Granada GENyO, Pfizer-University of Granada-Andalusian Regional Government Centre for Genomics and Oncological Research, Avenida de la Ilustración 114, 18016 Granada, Spain. 2. Department of Biochemistry and Molecular Biology I, Faculty of Science, University of Granada, Avenida Fuentenueva s/n, 18071 Granada, Spain. 3. Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain. (1)
1. Institut de Recherche en Immunologie et Cancérologie (IRIC), Université de Montréal, Montréal, Québec, Canada. 2. Département de Biochimie et Biologie Moléculaire, Université de Montréal, Montréal, Québec, Canada. 3. Département de Chimie, Université de Montréal, Montréal, Québec, Canada (1)
1. Translational Immunology Research Program, Transplantation Laboratory, University of Helsinki, Helsinki, Finland. 2. HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland (1)

Keyword

Checkpoint inhibitor (1)
Microbiome (1)
Pembrolizumab (1)
Ipilimumab (1)
Nivolumab (1)
Immunotherapy (1)

IsPrivate

False (15)

Model Flag

Non Kinetic (3)

Submitter Keywords

Immuno-oncology (3)
FROG (1)

Classification

bacteria (6)
fungi (2)
helminths (1)
protozoa (1)

Modification

4x(15)N labeled L-arginine (1)
Not available (1)

Study type

Transcription profiling by array (35)
Proteomic profiling by array (11)
RNA-seq of coding RNA (6)
Methylation profiling by high throughput sequencing (5)
RNA-seq of coding RNA from single cells (3)
Other (2)
Unknown experiment type (1)
Human - High-throughput sequencing (1)
Human - One-color microarray (1)
Comparative genomic hybridization by array (1)
MicroRNA profiling by array (1)
RNA-seq of total RNA (1)
RNA-seq of non coding RNA (1)
Observational (1)
Interventional (1)

Release Date

2022 (5737)
2023 (5116)
2021 (5095)
2025 (4813)
2024 (4242)
2020 (3833)
2019 (3115)
2018 (2771)
2017 (2377)
2016 (2316)
2015 (2116)
2014 (1836)
2013 (1118)
2012 (939)
2011 (814)
2010 (640)
2026 (549)
2009 (536)
2008 (409)
2007 (249)
2006 (174)
2005 (137)
2004 (77)
2003 (63)
2002 (48)
2001 (45)
2000 (39)
1998 (31)
1999 (30)
1997 (11)

Location

Canada (1)
United States (1)

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Changes in L-phenylalanine concentration reflect and predict response to anti-PD-1 treatment combined with chemotherapy in patients with non-small cell lung cancer

Chemotherapy combined with checkpoint blockade antibodies targeting programmed cell death protein (PD-1) has achieved remarkable success in non-small cell lung cancer (NSCLC). However, few patients benefit from long-term treatment. Therefore, biomarkers capable of guiding the optimal therapeutic sel...

2025-06-16 | MTBLS11232 | MetaboLights

Circulating cell populations as response predictors and targets to improve immunotherapy in metastatic lung cancer

The effectiveness of immunotherapy varies among patients with advanced non-small cell lung cancer (NSCLC). Here we investigated the baseline immune status in stage IV NSCLC patients treated with anti-PD-1 plus chemotherapy to understand the immune mechanisms and unveil systemic markers associated...

2025-10-16 | MTBLS13150 | MetaboLights

Complement Roles Revealed by Immune Gene Profiling in Endometriosis and Endometriosis-Associated Ovarian Cancer

Mechanisms of immune dysregulation against established tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear cell ovarian tumors may partly derive from endometriosis, a commonly diagnosed chronic inflamma...

ORGANISM(S): Homo sapiens

2015-01-07 | E-GEOD-57545 | biostudies-arrayexpress

Myelodysplastic Syndrome Revealed by Systems Immunology in a Melanoma Patient Undergoing Anti-PD-1 Therapy.

Not available

S-EPMC4891280 | biostudies-literature

Tumor immunology and cancer immunotherapy: summary of the 2014 SITC primer

Not available

S-EPMC4469248 | biostudies-literature

Report on the 2018 Cancer, Autoimmunity, and Immunology Conference.

Not available

S-EPMC7365167 | biostudies-literature

3D Culture Systems for Exploring Cancer Immunology.