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MetabolomicsMetabolic profiling of Candida clinical isolates of different species and infection sources

Candida species are the most common cause of opportunistic fungal infections. Rapid identification and novel approaches for the characterization of these fungi are of great interest to improve the diagnosis and the knowledge about their pathogenic properties. This study aimed to characte...

2024-07-09 | MTBLS1978 | MetaboLights
MetabolomicsThe Role of Annexin A1 in Candida albicans and Candida auris infections in murine neutrophils

Annexin A1 (AnxA1) is an anti-inflammatory protein present in different cells in biological systems, especially expressed in macrophages and neutrophils. Since neutrophils play an important role in infections and inflammatory processes and the AnxA1 and its relation in Candida spp. infections is ...

2021-12-03 | MTBLS2288 | MetaboLights
TranscriptomicsTelomeric ORFs (TLOs) in pathogenic Candida spp. encode Mediator subunits that regulate the transcription of distinct subsets of genes
Analysis of the role of the Candida dubliniensis Telomeric (TLO) genes and MED3, encoding subunits of Mediator, in regulating transcription The transcriptional response of a Candida dubliniensis TLO1/TLO2 double (null) mutant was analysed. Reintegrant strains harboring TLO1 or TLO2 were compared to ...
ORGANISM(S): Candida dubliniensis 
2014-07-11 | E-GEOD-59113 | biostudies-arrayexpress
GenomicsGenomic targets sites of the Candida glabrata transcription factor Pdr1
Pdr1 is the major regulator of azole resistance in the fungal pathogen Candida glabrata. Earlier experiments demonstrated that expression of Pdr1 itself is increased when cells lose their mitochondrial genome (rho0). Here we use chromatin immunoprecipitation coupled with highthroughput sequencing ...
ORGANISM(S): Candida glabrata CBS 138 
2014-09-12 | E-GEOD-59839 | biostudies-arrayexpress
TranscriptomicsTelomeric ORFs (TLOs) in Candida spp. encode Mediator subunits that regulate distinct virulence traits
Analysis of the interaction of Candida dubliniensis protein Tlo1p with DNA by ChIP-chip HA-tagged Tlo1p in Candida dubliniensis was used to identify Tlo1 interacting regions of DNA in global ChIP-chip analysis Experiment was carried out on cells grown at 30M-KM-^ZC in YEPD broth
ORGANISM(S): Candida dubliniensis 
2014-08-06 | E-GEOD-60173 | biostudies-arrayexpress
ProteomicsCandida albicans CUG codon translation, comparison with other yeasts
Candida yeasts causing human infections are spread across the yeast phylum with Candida glabrata being related to Saccharomyces cerevisiae, Candida krusei grouping to Pichia spp., and Candida albicans, Candida parapsilosis and Candida tropicalis belonging to the CTG-clade. The latter lineage contain...
ORGANISM(S): Candida albicans (Yeast) Candida albicans SC5314 Millerozyma acaciae Candida dubliniensis CD36 Candida tropicalis (Yeast) 
2021-11-17 | PXD027278 | Pride
Candida albicans Candida dubliniensis Candida tropicalis 
GenomicsCandida
Whole genome sequencing of candida spp.
PRJDB42621 | ENA
GenomicsHomo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)
Homo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)
PRJNA467610 | ENA
GenomicsHomo sapiens whole blood infected with Candida spp. (here: Candida glabrata)
Homo sapiens whole blood infected with Candida spp. (here: Candida glabrata)
PRJNA467612 | ENA
ProteomicsAntifungal Synergy: Mechanistic Insights into the R-1-R Peptide and Bidens pilosa Extract as Potent Therapeutics against Candida spp. through Proteomics
Previous work has reported that the peptide derived from LfcinB, R-1-R exhibited anti-Candida activity, which is enhanced when combined with an extract from the Bidens pilosa plant. However, the mechanism of action has not been studied until now. In the current study, an approach to the mechanism of...
ORGANISM(S): Candida albicans (Yeast) 
2024-10-17 | PXD053558 | Pride
Bovine lactoferricin peptides  bidens pilosa  candida albicans Proteomics Antifungal resistance. Disfunction mitochondrial Ros 
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