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GenomicsZfh1 ChIP-seq in Drosophila melanogaster embryos at 4-6h and 6-8h AEL
Canton S flies (as wild type) were bred at 25C and tightly staged 2-hr embryos were collected after 2 times of 2-hr prelay. The embryos were aged on the apple juice plates and aged to 4-6 and 6-8 hr. For each time point, two independent Chromatin immunoprecipitation (ChIP) experiments were performed...
ORGANISM(S): Drosophila melanogaster 
2019-07-01 | E-MTAB-7422 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiles in ovarian cancer linked to Lynch syndrome
Heredity is a major cause of ovarian cancer. Lynch syndrome is associated with 10-12% risk of ovarian cancer, diagnosis at young age and a predilection for endometrioid and clear cell tumors. Global gene expression profiling applied to 25 Lynch syndrome-associated and 42 sporadic ovarian cancers rev...
ORGANISM(S): Homo sapiens 
2013-10-14 | E-GEOD-37394 | biostudies-arrayexpress
TranscriptomicsThe microstructural, mineralogical and transcriptional developments of shell biomineralization of Pinctada maxima
Molluscan larval ontogeny is a highly conserved process typical of 3 principal developmental stages. A characteristic unique to each of these stages is shell design, termed prodissoconch I, prodissoconch II and dissoconch. These shells vary in morphology, mineralogy and microstructure. The discrete ...
ORGANISM(S): Pinctada maxima 
2010-02-04 | E-GEOD-14305 | biostudies-arrayexpress
TranscriptomicsHDAC Inhibitors induce tumor cell-selective pro-apoptotic transcriptional responses.
The identification of recurrent somatic mutations in genes encoding epigenetic enzymes, coupled with biochemical studies demonstrating aberrant recruitment of epigenetic enzymes such as histone deacetylases (HDACs) and histone methyltransferases (HMTs) to promoter regions through association with on...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-43010 | biostudies-arrayexpress
UnknownDNGR-1 signalling limits dendritic cell activation for optimal antigen cross-presentation
Not available
S-SCDT-10_1038-S44318-025-00620-Z | biostudies-other
TranscriptomicsKidney development time course
Array Design; Mouse Compugen 22K Spotted Oligo Author; Sean Grimmond Common Reference (Yes/No, ID); Yes Mouse universal Reference (Stratagene) Concentration; 100 Data processing/normalization; Lowess Normalisation GeneSpring) Developmental Stage; embryonic Diseased/Normal; normal Dye Swap; red/green...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2282 | biostudies-arrayexpress
TranscriptomicsRNA Sequencing Quantitative Analysis and identification of RNA editing sites of Wild Type and ADAR1 editing deficient (ADAR1E861A) murine fetal liver RNA
Purpose: RNA editing by ADAR1 is essential for hematopoietic development. The goals of this study were firstly, to identify ADAR1-specific RNA-editing sites by indentifying A-to-I (G) mismatches in RNA-seq data compared to mm9 reference genome in wild type mice that were not edited or reduced in edi...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-58917 | biostudies-arrayexpress
TranscriptomicsDNA methylation differences between human regulatory T cells and conventional T cells
Regulatory T cells (Treg) prevent the emergence of autoimmune disease. Prototypic natural Treg (nTreg) are programmed by Forkhead-box P3 (FOXP3) and can be reliably identified by demethylation at the FOXP3 locus. To explore the nTreg methylation landscape we performed genome-wide methylation studies...
ORGANISM(S): Homo sapiens 
2013-09-09 | E-GEOD-49667 | biostudies-arrayexpress
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