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UnknownIncidence of cancer and related deaths in hemoglobinopathies: A follow-up of 4631 patients between 1970 and 2021.
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S-EPMC10092274 | biostudies-literature
Transcriptomicssingle cell RNA sequencing of 120h mouse gastruloids cultured with different doses of retinol
We quantified the effects of retinol on the cell type composition of gastruloids at 120 hours after aggregation by single cell RNA sequencing (scRNA-seq). Gastruloids were generated from the Rarb2.LacZ reporter cell line and cultured according to the standard protocol and few modifications: - cultu...
ORGANISM(S): Mus musculus 
2026-07-24 | E-MTAB-17398 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus mRNA-sequencing reveals dynamics of lipogenic and thermogenic adipocyte populations in murine brown adipose tissue in response to cold exposure
Brown adipocyte-specific ChREBP knockout were generated by crossing mice with a floxed exon1a in the Mlxipl gene with Ucp1-Cre mice. These ChREBPflox/flox Ucp1-Cre+ (Cre+) mice and ChREBP-expressing control (Cre-) mice were studied under various conditions of BAT activation. Housing at room temperat...
ORGANISM(S): Mus musculus 
2025-11-10 | E-MTAB-15819 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of mouse EpiSCs (epiblast stem cells) differentiated to extraembryonic mesoderm in vitro, in a monolayer
EpiSCs derived from epiblast of a gastrulating embryo differentiated towards extraembryonic mesoderm to test the efficiency of the differentiation protocol and identity and homogeneity of the resulting cell population.
ORGANISM(S): Mus musculus 
2022-11-30 | E-MTAB-12107 | biostudies-arrayexpress
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
TranscriptomicsscRNA-seq for mEpiSCs (epiblast stem cells) differentiated to posterior primitive streak (PPS) in vitro, in a monolayer
EpiSCs established from murine epiblast were differentiated to posterior primitive streak (PPS) and analyzed using scRNA-seq to investigate identity and homogeneity of the resulting population.
ORGANISM(S): Mus musculus 
2022-11-30 | E-MTAB-12106 | biostudies-arrayexpress
TranscriptomicsCUT&RUN LoV-U of beta-catenin, TCF/LEF transcription factors and histone modifications in HEK293T and mouse embryonic hindlimb tissue at 11.5 days post coitum
In our attempts to profile different regulators of the WNT/b-catenin transcriptional complex, CUT&RUN failed to produce consistent binding patterns of the non-DNA-binding b-catenin. We developed a modified CUT&RUN protocol, which we refer to as LoV-U (Low Volume and Urea), that enables the generatio...
ORGANISM(S): Mus musculus 
2022-07-16 | E-MTAB-11951 | biostudies-arrayexpress
TranscriptomicssnRNA-seq of cortices from a MCT8-OATP1C1-deficient Allan-Herndon-Dudley Syndrome mouse model
Allan-Herndon-Dudley syndrome (AHDS) is a rare disorder caused by faulty thyroid hormone transport to the brain, leading to severe movement problems and intellectual disability. Our study in a murine model of the AHDS used snRNAseq to gain deep insights into individual cortical cells, aiming to unra...
ORGANISM(S): Mus musculus 
2026-08-07 | E-MTAB-16567 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human intestinal organoids infected with Salmonella enterica at 2.5h and 8h post infection
The purpose of this experiment was to identify intestinal epithelial responses to various strains of Salmonella enterica. Human intestinal organoids were infected with three serovars of Salmonella; Typhimurium, Enteritidis and Typhi, as well as type 3 secretion system -1 and -2 mutants in Typhimuriu...
ORGANISM(S): Homo sapiens 
2021-10-01 | E-MTAB-10451 | biostudies-arrayexpress
TranscriptomicsATAC-seq of human embryonic stem cells during cell cycle progression
The experiment was designed to look into chromatin accessibility changes during cell cycle progression in human embryonic stem cells (hESCs). For this, FUCCI hESCs are sorted in Early G1 (EG1), Late G1 (LG1), G1/S transition and S/G2/M phases in duplicates. 100,000 were used per sample, as described...
ORGANISM(S): Homo sapiens 
2023-06-24 | E-MTAB-8348 | biostudies-arrayexpress
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