Sort   by:  
 Page size 
MetabolomicsZingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of Sat1 and Gpx4 expression

Zingerone, a component of dried ginger, has known anti-ulcer and bone growth-promoting effects, but its impact on postmenopausal osteoporosis (PO) is unclear. This study investigates the therapeutic potential and underlying mechanisms of zingerone in PO. A concentration-dependent effect identifie...

2025-08-07 | MTBLS12829 | MetaboLights
TranscriptomicsComparison of the metabolic response to over-production of p-coumaric acid in two yeast strains
We aimed to study how production of p-coumaric acid, a precursor of multiple secondary aromatic metabolites, influences the cellular metabolism of Saccharomyces cerevisiae. We evaluated the growth and p-coumaric acid production in batch and chemostat cultivations and analyzed the transcriptome and i...
ORGANISM(S): Saccharomyces cerevisiae 
2017-11-21 | E-MTAB-6208 | biostudies-arrayexpress
TranscriptomicsBrassica nigra challenged by Pieris brassicae, eggs of Pieris brassicae, Xanthomonas campestris pv. raphani, Brevicoryne brassicae or by combined stresses eggs of P. brassicae / P. brassicae, X. campestris / P. brassicae, B. brassicae / P. brassicae
Brassica nigra plants, a Brassicaceae close to Arabidopsis thaliana, was used for combined stresses experiments. In this study, we performed a whole-genome microarray analysis on five-week-old plants and compared untreated plants and plants treated different single or dual stresses: the larvae Pieri...
ORGANISM(S): Brassica nigra 
2017-03-31 | E-MTAB-5059 | biostudies-arrayexpress
ProteomicsMethionine Restriction Alleviates Kidney Fibrosis through Epigenetic Repression of the TGF-β-Smad3-Hoxc8/P-TEFb axis
Low-protein diets can mitigate renal fibrosis, yet the critical amino acid responsible for this benefit and its underlying mechanism remain unclear. By screening 15 amino acid–restricted diets in a unilateral ureteral obstruction (UUO) model, we identify methionine restriction (MetR) as the most eff...
ORGANISM(S): Homo sapiens (Human) 
2025-12-04 | PXD071531 | Pride
Kidney fibrosis  methionine restriction  hoxc8  p-tefb 
GenomicsGenome-wide map of RNA polymerase II, NELF, and DSIF in HeLa cells
Most metazoan promoters have RNA polymerase II (Pol II) paused slightly downstream of the transcription start site by NELF and DSIF. This pausing keeps these promoters available for rapid induction by P-TEFb, whose activity causes NELF to dissociate and Pol II and DSIF to elongate on the gene. ChIP-...
ORGANISM(S): Homo sapiens 
2014-02-01 | E-GEOD-53008 | biostudies-arrayexpress
UnknownAb initio investigation of CaO-ZnO alloys under high pressure.
Not available
S-EPMC4505315 | biostudies-literature
TranscriptomicsDistinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: ChIP-chip]
We performed a set of microarray and chromatin-immunoprecipitation (ChIP)-chip experiments using siRNA against the (pro)renin receptor ((P)RR), stable overexpression of PLZF, the PLZF translocation inhibitor genistein and the specific V-ATPase inhibitor bafilomycin to dissect transcriptional pathway...
ORGANISM(S): Homo sapiens 
2013-07-05 | E-GEOD-39960 | biostudies-arrayexpress
TranscriptomicsBrassica nigra challenged by ozone, Pieris brassicae and both ozone followed by P. brassicae feeding.
Brassica nigra plants, a Brassicaceae close to Arabidopsis thaliana, was used for combined stresses experiments. In this study, we performed a whole-genome microarray analysis on five-week-old plants and compared untreated plants and plants treated with ozone at 70 ppb, larvae of Pieris brassicae or...
ORGANISM(S): Brassica nigra 
2017-02-10 | E-MTAB-5030 | biostudies-arrayexpress
UnknownNovel procedure of CO2 capture of the CaO sorbent activator on the reaction of one-part alkali-activated slag.
Not available
S-EPMC8696962 | biostudies-literature
UnknownThe complete mitochondrial genome of Triplophysa nanpanjiangensis Zhu and Cao 1988 (Cypriniformes: Nemacheilidae).
Not available
S-EPMC10776044 | biostudies-literature
Sort   by:  
 Page size