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TranscriptomicsEffect of Bicaudal C1 deletion on E13.5 mouse pancreatic mRNA profile
Bicaudal C1 KO embryonic pancreas develops cysts and has less endocrine progenitors after E14.5 (14.5 days after fertilization), while no defect is observed at E13.5. Bicaudal C1 is an RNA-binding protein. To understand the molecular mechanisms leading to both phenotypes, the mRNA expression profile...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-58833 | biostudies-arrayexpress
TranscriptomicsIdentification by ChIP-on-Chip of ARX target genes, a transcription factor implicated in mental retardation and epilepsy
Genetic investigations of X-linked intellectual disabilities have implicated the ARX (Aristaless-related homeobox) gene in a wide spectrum of disorders extending from phenotypes characterised by severe neuronal migration defects such as lissencephaly, to mild or moderate forms of mental retardation ...
ORGANISM(S): Mus musculus 
2011-12-22 | E-GEOD-29985 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression between Arx-transfected N2a cells and cells transfected by the corresponding empty vector
Genetic investigations of X-linked intellectual disabilities have implicated the ARX (Aristaless-related homeobox) gene in a wide spectrum of disorders extending from phenotypes characterised by severe neuronal migration defects such as lissencephaly, to mild or moderate forms of mental retardation ...
ORGANISM(S): Mus musculus 
2011-12-22 | E-GEOD-30190 | biostudies-arrayexpress
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