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ProteomicsPerturbations of hepatic proteome behind the onset of metabolic disorders in mouse offspring developed following assisted reproductive technologies
Background: Assisted Reproductive Technologies (ART) - treatments to allow parenthood to couples facing fertility issues- have allowed the birth of > 5 million babies worldwide. Notwithstanding most of ART children are healthy at birth, several studies reported that ART may affect early-life experie...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-05-14 | MSV000085413 | MassIVE
MetabolomicsCross-modal Integration of Metabolomics and Cardiac Functionality Captures Dynamic Metabotoxic Effects of Doxorubicin in Engineered Heart Tissues

Functional stem cell-derived heart models offer new avenues for preclinical, animal-free physiological assessment of drug cardiotoxicity. Yet, comprehensive molecular profiling in these models remains limited, leaving key metabolic drivers of cardiotoxicity unexplored.

Here, we leveraged an...

2025-12-07 | MTBLS13225 | MetaboLights
ProteomicsMetaproteomic study about diet-induced effects on the gut microbiota of patients affected by Crohn's disease
Metaproteomic study on fecal samples collected from Crohn's Disease (CD) patients and some Household Healthy Controls (HHC) during an eight week Lof Fat/High fiber diet intervention. Stoo sampling was performed at baseline (V1), week 8 (V2) and week 36 (V3). Protein Identification and quantitation ...
ORGANISM(S): Bacteria Homo Sapiens (ncbitaxon:9606) 
2024-02-01 | MSV000093975 | MassIVE
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