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MetabolomicsSynergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation

Bacterial metabolism in oral biofilms is comprised of complex networks of nutritional chains and biochemical regulations. These processes involve both intraspecies and interspecies networks as well as interactions with components from host saliva, gingival crevicular fluid, and dietary intake. In...

2023-10-30 | MTBLS8370 | MetaboLights
MetabolomicsChitin utilization by marine picocyanobacteria and the evolution of a planktonic lifestyle.
Marine picocyanobacteria Prochlorococcus and Synechococcus, the most abundant photosynthetic cells in the oceans, are generally thought to have a primarily single-celled and free-living lifestyle. However, while studying the ability of picocyanobacteria to supplement photosynthetic car...
2024-02-21 | MTBLS5229 | MetaboLights
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (miRNA)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63559 | biostudies-arrayexpress
MetabolomicsUntargeted extraction of metabolites 13C labeling profiles from time course labeling switch experiment
Dynamic isotope labeling data provide crucial information about the operation of metabolic pathways, and are commonly generated via liquid chromatography mass spectrometry (LC-MS). Metabolome-wide analysis is challenging as it requires grouping of metabolite features over different samples. We devel...
2015-10-19 | MTBLS228 | MetaboLights
OtherSystems-based analysis of Arabidopsis leaf growth reveals adaptation to water deficit.
PRIDE ID: 21331, ae1_5: PE47_1, PE48_1, PE5_4, PE6_4, PE7_4, PE8_4, control_25, control_26. Data published as part of Mol Syst Biol. 2012, 8:606 . From the Abstract: {{i}} ... To reveal the dynamic systems behaviour of leaf development, we profiled Arabidopsis leaf number six in depth at four diffe...
ORGANISM(S): Thale_cress 
GPM11210004321 | GPMDB
Resource Reanalysis 
TranscriptomicsFast Growth Increases the Selective Advantage of a Mutation Arising Recurrently during Evolution under Metal Limitation
The goal was to use microarray to compare changes in the global transcription profiles between an engineered bacterial strain and one of its descendants subject to 600 generations of experimental evolution in batch culture. This comparison allowed us to identify a beneficial mutation that substantia...
ORGANISM(S): Methylobacterium extorquens AM1 
2010-06-20 | E-GEOD-14875 | biostudies-arrayexpress
ProteomicsOstreococcus OlV1/OlV7 lysate DOM
Dissolved organic matter extracts prepared by viral lysates of Ostreococcus lucimarinus CCMP2972, infected by lytic viruses OlV1 and OlV7, as well as uninfected controls, under standard-light (~110uE/m2s; "SL") and low-light (15uE/m2s, "LL") irradiance.
ORGANISM(S): Ostreococcus Lucimarinus Cce9901 (ncbitaxon:436017) Ostreoccus Lucimarinus Virus Olv7 Ostreococcus Lucimarinus Virus 1 (ncbitaxon:880162) 
2019-02-12 | MSV000083434 | MassIVE
TranscriptomicsThe VELVET complex in the gray mold fungus Botrytis cinerea: impact of BcLAE1 on differentiation, secondary metabolism and virulence
Full transcriptomes of the Botrytis cinerea wild-type strain B0510 and the null-mutants deltaBcVEL1 and deltaBcLAE1, cultured onto solid grape juice medium with cellophane overlays , were compared to identify BcVEL1 or/and BcLAE1-dependent genes. The Botrytis cinerea wild-type strain and the null-m...
ORGANISM(S): Botrytis cinerea 
2015-02-01 | E-GEOD-63021 | biostudies-arrayexpress
TranscriptomicsIpsA, a novel transcriptional regulator required for inositol derived lipid formation in Corynebacteria and Mycobacteria
The development of new drugs against tuberculosis and diphtheria is focused on disrupting the biogenesis of the cell wall, the unique architecture of which confers resistance against current therapies. The enzymatic pathways involved in the synthesis of the cell wall by these pathogens are well unde...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2014-01-13 | E-GEOD-50210 | biostudies-arrayexpress
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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