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TranscriptomicsSubtypes of HPV-positive head and neck cancers are associated with HPV characteristics, copy number variations, PIK3CA mutation, and pathway signatures. [RNA-Seq]
Purpose: There is substantial heterogeneity within the human papillomavirus (HPV) positive head and neck cancer (HNC) tumors that predispose them to different outcomes, however this subgroup is poorly characterized due to various historical reasons. Experimental Design: we perform unsupervised gene...
ORGANISM(S): Homo sapiens 
2016-05-13 | E-GEOD-74927 | biostudies-arrayexpress
MetabolomicsInferring metabolic mechanisms of interaction within a defined gut microbiota
The diversity and number of species present within microbial communities create the potential for a multitude of interspecies metabolic interactions. Here, we develop, apply, and experimentally test a framework for inferring metabolic mechanisms associated with interspecies interactions. We perform ...
2019-10-29 | MTBLS705 | MetaboLights
TranscriptomicsEpigenome analysis in HPV(-) and HPV(+) squamous cell carcinoma cell lines
Human papillomavirus (HPV)-associated head and neck cancers (HNSCCs) have a distinct risk profile and appreciate a prognostic advantage compared to HPV-negative HNSCC. Promoter hypermethylation has been widely recognized as an important mechanism in the progression of HNSCC, but the extent to which ...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-24087 | biostudies-arrayexpress
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