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TranscriptomicsGene expression profiles in resistant acute lymphoblastic leukemia
Treatment resistance as indicated by the presence of high levels of minimal residual disease (MRD) after induction therapy and induction consolidation is associated with a poor prognosis in childhood acute lymphoblastic leukemia (ALL). We hypothesized that treatment resistance is an intrinsic featur...
ORGANISM(S): Homo sapiens 
2006-01-18 | E-GEOD-4057 | biostudies-arrayexpress
TranscriptomicsExpression data from proximal jejunum of WT vs. TLR2 KO mice after methotrexate (MTX) treatment
The role of innate immunity in modulating severity of chemotherapy-induced complications is so far unclear. The aim of this study was to determine how TLR2 may influence MTX-induced mucositis in the small intestine in mice. We used microarrays to assess gene expression profiles in proximal jejunum o...
ORGANISM(S): Mus musculus 
2015-01-24 | E-GEOD-56426 | biostudies-arrayexpress
UnknownMethotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen.
Not available
S-EPMC7109740 | biostudies-literature
TranscriptomicsExpression data from Caco-2 cells expressing TLR4 and associated mutants
Common missense mutations (D299G, T399I) have been recently identified in the human TLR4 gene. The aim of this study was to determine how TLR4 and associated mutants affect gene expression in Caco-2 cells. We used microarrays to asses gene expression profiles in Caco-2 stably overexpressing TLR4-WT,...
ORGANISM(S): Homo sapiens 
2011-10-10 | E-GEOD-26226 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of resistant acute lymphoblastic leukemia ALL
Treatment resistance as indicated by the presence of high levels of minimal residual disease (MRD) after induction therapy and induction consolidation is associated with a poor prognosis in childhood acute lymphoblastic leukemia (ALL). We hypothesized that treatment resistance is an intrinsic featur...
ORGANISM(S): Homo sapiens 
2005-11-09 | E-SMDB-2922 | biostudies-arrayexpress
UnknownShwachman-Diamond syndrome due to biallelic EFL1 variants with complex and fatal clinical course in early infancy.
Not available
S-EPMC11637716 | biostudies-literature
UnknownTranscriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics.
Not available
S-EPMC8616234 | biostudies-literature
TranscriptomicsTranscription profiling of human Downs syndrome with acute lymphoblastic pediatric leukemia (DS-ALL) patients
DS-ALL is a highly heterogeneous disease with predominance of an aberrant exp. of CRLF2 cooperating with mutated JAK2; Acute lymphoblastic pediatric leukemia specimens of Down's syndrome are examined for gene expression profiles and specific genetic aberrations. Gene expression profiling and specifi...
ORGANISM(S): Homo sapiens 
2010-01-15 | E-GEOD-17459 | biostudies-arrayexpress
TranscriptomicsPurified intestinal epithelial cells from foetal and paediatric gut
CD326+ sorted intestinal epithelial cells from foetal (9-12 wk gestational age) small bowel and large bowel, CD326+ sorted intestinal epithelial cells from mucosal biopsies of paediatric (5-15 years of age) terminal illeum, ascending colon and sigmoid colon FPG=Foetal proximal gut, FDG=Foetal distal...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-MTAB-3703 | biostudies-arrayexpress
TranscriptomicsPurified intestinal epithelial cells from foetal and paediatric gut
CD326+ sorted intestinal epithelial cells from foetal (9-12 wk gestational age) small bowel and large bowel, CD326+ sorted intestinal epithelial cells from mucosal biopsies of paediatric (5-15 years of age) terminal illeum, ascending colon and sigmoid colon FPG=Foetal proximal gut, FDG=Foetal distal...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-MTAB-3704 | biostudies-arrayexpress
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