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MetabolomicsGut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia
Familial dysautonomia (FD) is a rare genetic neurologic disorder caused by impaired neuronal development and progressive degeneration of both the peripheral and central nervous systems. FD is monogenic, with >99.4% of patients sharing an identical point mutation in the elongator acetyltransferase co...
2022-12-06 | MTBLS5138 | MetaboLights
UnknownThe Breast Health Global Initiative 2018 Global Summit on Improving Breast Healthcare Through Resource-Stratified Phased Implementation: Methods and overview.
Not available
S-EPMC7482869 | biostudies-literature
TranscriptomicsDm_y[1]cn[1] bw[1] sp[1]_embryo_4-6h_poly-Ap_p200_409-410-411_38bp
modENCODE_submission_121 This submission comes from a modENCODE project of Susan Celniker. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will generate over 600 RNA samples in biological triplicate and use them to generate expression profile maps detailing t...
ORGANISM(S): Drosophila melanogaster 
2010-08-04 | E-GEOD-23219 | biostudies-arrayexpress
TranscriptomicsDm_y[1]cn[1] bw[1] sp[1]_embryo_6-8h_TotalRNA_p200_230-232_38bp
modENCODE_submission_763 This submission comes from a modENCODE project of Susan Celniker. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will generate over 600 RNA samples in biological triplicate and use them to generate expression profile maps detailing t...
ORGANISM(S): Drosophila melanogaster 
2010-08-04 | E-GEOD-23230 | biostudies-arrayexpress
TranscriptomicsDm_y[1]cn[1] bw[1] sp[1]_pupa_WhitePrePupaep2days_TotalRNA_p200_344-346-348_38bp
modENCODE_submission_541 This submission comes from a modENCODE project of Susan Celniker. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will generate over 600 RNA samples in biological triplicate and use them to generate expression profile maps detailing t...
ORGANISM(S): Drosophila melanogaster 
2010-08-04 | E-GEOD-23223 | biostudies-arrayexpress
TranscriptomicsIdentification of protein-RNA interactions in Drosophila using RIP-Seq
The goal of these experiments is to identify RNAs bound by individual RNA-binding proteins. Drosophila S2R+ cells were transiently transfected with vectors encoding the indicated HA-tagged RNA-binding proteins, or without an insert as a control. Expression was induced with CuSO4, whole cell lysates ...
ORGANISM(S): Drosophila melanogaster 
2012-05-05 | E-GEOD-37756 | biostudies-arrayexpress
GenomicGroup Health/UW Aging and Dementia eMERGE Study

The "Development and Use of Network Infrastructure for High-Throughput GWA Studies" project is collaboration between Group Health Cooperative (GH), the University of Washington (UW), and the Fred Hutchinson Cancer Research Center (FHCRC). It is one of 5 sites participating in The Electronic Medic...

phs000234 | dbGaP
UnknownEstrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Not available
S-EPMC4821807 | biostudies-literature
UnknownThe SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Not available
S-EPMC6335054 | biostudies-literature
UnknownAntagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.
Not available
S-EPMC6469989 | biostudies-literature
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