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TranscriptomicsRole of the Yersinia pestis Virulence Plasmid in Evading a Protective Polymorphonuclear Leukocyte Response During the Early Stages of Bubonic Plague
A delay in the mammalian inflammatory response is a prominent feature of infection with Yersinia pestis, the agent of bubonic and pneumonic plague. Y. pestis factors have been identified that either do not stimulate a normal inflammatory response, or actively suppress it. Prominent among these are c...
ORGANISM(S): Rattus norvegicus 
2010-12-07 | E-GEOD-22299 | biostudies-arrayexpress
TranscriptomicsInteractome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus
Relatively little is understood about the dynamics of global host–pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes a host transcriptome response, we performed genom...
ORGANISM(S): Macaca fascicularis 
2010-03-18 | E-GEOD-20262 | biostudies-arrayexpress
TranscriptomicsIntracellular proliferation and virulence gene expression of Salmonella are influenced by pre-invasion growth conditions
Salmonella invasion of non-phagocytic cells is a dynamic process that requires the translocation of effector proteins into host cells by a type III secretion system (T3SS1) encoded on Salmonella pathogenicity island 1 (SPI1). The signals involved in T3SS1 induction in vivo are not known, but SPI1-in...
ORGANISM(S): Salmonella typhimurium SL1344 
2010-04-19 | E-GEOD-13343 | biostudies-arrayexpress
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