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GenomicsHigh-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm
Mammalian embryonic stem (ES) cells and sperm exhibit unusual chromatin packaging that plays important roles in cellular function. Here, we extend a recently developed technique, based on deep paired-end sequencing of lightly digested chromatin, to assess footprints of nucleosomes and other DNA-bind...
ORGANISM(S): Mus musculus 
2014-07-08 | E-GEOD-58101 | biostudies-arrayexpress
TranscriptomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals
This SuperSeries is composed of the following subset Series: GSE25895: Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (dye swap) GSE25896: Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammal...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25899 | biostudies-arrayexpress
TranscriptomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (Affymetrix)
Epigenetic information can be inherited through the mammalian germline, and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental information occurs in mammals, we carried out an expression profiling screen for g...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25896 | biostudies-arrayexpress
TranscriptomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (dye swap)
Epigenetic information can be inherited through the mammalian germline, and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental information occurs in mammals, we carried out an expression profiling screen for g...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25895 | biostudies-arrayexpress
TranscriptomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (small RNA)
Characterized the small (19-35 bp) RNA population from control and low protein offspring livers by high throughput sequencing. Eight sequencing lanes, one for each animal, with an average of 3.7 million mappable reads per lane. A number of miRNAs changed expression in the offspring from low protein ...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25897 | biostudies-arrayexpress
GenomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (meDIP)
Epigenetic information can be inherited through the mammalian germline, and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental information occurs in mammals, we carried out an expression profiling screen for g...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25898 | biostudies-arrayexpress
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