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Allan-Herndon-Dudley syndrome (AHDS) is a rare disorder caused by faulty thyroid hormone transport to the brain, leading to severe movement problems and intellectual disability. Our study in a murine model of the AHDS used snRNAseq to gain deep insights into individual cortical cells, aiming to unra...
ORGANISM(S): Mus musculus 
BAT transcriptome from control and brown adipocyte-specific Rev-erbα/β double knockout mice housed at thermoneutrality or cold-challenged for 6 hours. Brown adipose tissue (BAT) samples were collected from control and brown adipocyte-specific Rev-erbα/β double knockout mice (Ucp1-Cre; Nr1d1/2 fl/fl)...
ORGANISM(S): Mus musculus 
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
Abnormal development of the prefrontal cortex (PFC) is associated with a number of neuropsychiatric disorders that have an onset in childhood or adolescence. Although the basic laminar structure of the PFC is established in utero, extensive remodeling continues into adolescence. To map the overall p...
ORGANISM(S): Mus musculus 
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