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TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
BAT transcriptome from control and brown adipocyte-specific Rev-erbα/β double knockout mice housed at thermoneutrality or cold-challenged for 6 hours. Brown adipose tissue (BAT) samples were collected from control and brown adipocyte-specific Rev-erbα/β double knockout mice (Ucp1-Cre; Nr1d1/2 fl/fl)...
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17580 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17577 | biostudies-arrayexpress
TranscriptomicsHeLa cells treated with V-ATPase inhibitors or with desoxyferramine compared to HeLa in DMSO or medium with low LDL
Expression data from HeLa cells treated with V-ATPase inhibitors or with desoxyferramine compared to HeLa treated with DMSO or medium with low LDL To determine which genes respond first to low concentrations of V-ATPase inhibition, we treated HeLa cells with two different V-ATPase inhibitors, bafil...
ORGANISM(S): Homo sapiens 
2010-07-22 | E-GEOD-16870 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of genes impacted by 5 day knockdown of SLC24A5 in normal human melanocytes.
A major development in pigmentation research was the discovery of the involvement of SLC24A5 in natural variation in skin colour. This study used Agilent whole-genome microarrays to examine the impact of SLC24A5 knockdown on the transcriptome of normal human melanocytes derived from lightly and dark...
ORGANISM(S): Homo sapiens 
2012-04-25 | E-GEOD-21565 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis to identify genes involved in the induction of storage reserve mobilisation
Aim To identify genes specifically involved in the storage reserve mobilisation programme in Arabidopsis. Background During germination and early post-germinative growth in Arabidopsis seed storage reserves are broken down to provide energy and nutrients for the developing seedling. Genes encodin...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6173 | biostudies-arrayexpress
MetabolomicsOmics data integration allows the identification of an idiopathic Parkinson’s disease signature
The vast majority of Parkinson’s disease cases are idiopathic. Unclear ethiology and multifactorial nature complicate the comprehension of disease pathogenesis. Identification of early transcriptomic and metabolic alterations consistent across different idiopathic Parkinson’s disease (IPD) patients ...
2026-03-16 | MTBLS7740 | MetaboLights
TranscriptomicsRNA-Seq in liver of Tc1 mice carrying human chromosome 21 passaged through either the female or male germline
This study aims to investigate whether the passage of human chromosome 21 through the mouse male germline results in changes in the transcriptional deployment of the exogenous chromosome in the offspring generation. We used the Tc1 mouse model that stably carries almost an entire copy of human chrom...
ORGANISM(S): Mus musculus 
2016-11-16 | E-MTAB-4912 | biostudies-arrayexpress
GenomicsBioCAP-Seq analysis of human chromosome 21 after its passage through either the mouse male germline
This study aims to investigate whether the passage of human chromosome 21 through the mouse male germline results in changes in the transcriptional deployment of the exogenous chromosome in the offspring generation. We used the Tc1 mouse model that stably carries almost an entire copy of human chrom...
ORGANISM(S): Mus musculus 
2016-11-16 | E-MTAB-4930 | biostudies-arrayexpress
TranscriptomicsCaste-specific expression patterns of olfactory related genes in the leaf-cutting ant, Atta vollenweideri
To allow estimation of the complexity and gene expression differences of the antennal transcriptome between sexes as well as between castes, microarrays were designed based on an assembly of A. vollenweideri antennal sequence data from all sexes and castes. The microarrays were hybridized with sampl...
ORGANISM(S): Atta vollenweideri 
2013-10-01 | E-GEOD-48824 | biostudies-arrayexpress
TranscriptomicsAntigen availability determines CD8+ T cell-dendritic cell interaction kinetics and T cell fate decisions.
This experiment compares the transciptional changes in antigen specific murine CD8 T cells (P14 T cells) after exposure in vivo to dendritic cells (DC) pulsed with low dose cognate peptide (1uM KAVYNFATC), high dose cognate peptide (100uM KAVYNFATC) or no antigen. Splenic dendritic cells were freshl...
ORGANISM(S): Mus musculus 
2013-11-21 | E-GEOD-49274 | biostudies-arrayexpress
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