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TranscriptomicsGenome-wide analysis of SIK2 regulated genes and pathways
Identification of SIK2 regulated genes and pathways after SIK2 knock-down and overexpression of a wild-type and kinase-dead SIK2. The hypothesis is that SIK2 regulated gene expression via CREB1 Total RNAs were obtained after SIK2 gene was knocked down with siRNA and after a wild-type SIK2 or a kinas...
ORGANISM(S): Homo sapiens 
2015-01-12 | E-GEOD-45711 | biostudies-arrayexpress
GenomicsHes6 drives a critical AR transcriptional program to induce castration resistant prostate cancer through activation of an E2F1-mediated cell cycle network
Castrate-resistant prostate cancer (CRPC) is poorly characterized and heterogeneous and while the androgen receptor (AR) is of singular importance, other factors such as c-Myc and the E2F family also play a role in later stage disease. Here we show that Hes6 is up-regulated in aggressive human prost...
ORGANISM(S): Homo sapiens 
2014-04-17 | E-GEOD-49832 | biostudies-arrayexpress
UnknownDasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.
Not available
S-EPMC6067800 | biostudies-literature
UnknownT cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
Not available
S-EPMC11527131 | biostudies-literature
UnknownT cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
Not available
S-EPMC12312045 | biostudies-literature
TranscriptomicsExpression data from wildtype and Dicer-deficient mouse embryonic stem (ES) cells at different stages of the cell cycle.
The protein Dicer is required for microRNA (miRNA) biogenesis. Dicer-deficient cells therefore lack almost all mature, functional miRNAs. We investigated the role of miRNAs in regulation of gene expression in mouse ES cells by analysing gene expression in either wildtype or Dicer-deficient cells gro...
ORGANISM(S): Mus musculus 
2016-06-02 | E-GEOD-60096 | biostudies-arrayexpress
UnknownTrans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine.
Not available
S-EPMC4113935 | biostudies-literature
UnknownBooster Vaccination Against SARS-CoV-2 Induces Potent Immune Responses in People With Human Immunodeficiency Virus.
Not available
S-EPMC9619587 | biostudies-literature
UnknownPhysical and psychosocial impact on peers with HIV co-leading an HIV intervention: A pilot theory-guided case-study.
Not available
S-EPMC10194128 | biostudies-literature
UnknownDurability of ChAdOx1 nCoV-19 vaccination in people living with HIV.
Not available
S-EPMC9057612 | biostudies-literature
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