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MetabolomicsDetection Limits of Blood Metabolites at Physiological Concentrations Using Benchtop 1H NMR

Commercial low-field (LF) magnetic resonance spectroscopy (MRS) offers a route to rapid and repeated \textit{in vivo} metabolite tracking, however its sensitivity and interpretability at physiological concentrations remain underexplored. Here we evaluate the performance of an 80 MHz benchtop nucl...

2025-12-29 | MTBLS6262 | MetaboLights
TranscriptomicsscRNA-seq analysis of enriched CD4+ T cells from lung tissues after single or combined AIT treatment strategies with AhR agonist 10-Cl-BBQ in a murine model of OVA-induced allergic airway inflammation (AAI)
Allergen-specific immunotherapy (AIT) is able to restore immune tolerance to allergens in allergic patients. However, some patients do not or only poorly respond to current treatment protocols. Therefore, there is a need for deeper mechanistic insights and further improvement of treatment strategies...
ORGANISM(S): Mus musculus 
2024-05-06 | E-MTAB-14030 | biostudies-arrayexpress
TranscriptomicsmRNAseq of human sputum macrophages and alveolar-like monocyte-derived macrophages of healthy controls and NSAID-exacerbated respiratory disease (N-ERD) patients
NSAID-exacerbated respiratory disease (N-ERD) represents a particularly severe endotype of chronic rhinosinusitis with nasal polyps (CRSwNP), which affects around 10-16% of CRSwNP patients. N-ERD is characterized by severe and refractory nasal polyposis, bronchial asthma and intolerance to non-stero...
ORGANISM(S): Homo sapiens 
2020-06-30 | E-MTAB-7965 | biostudies-arrayexpress
TranscriptomicsTotal RNAseq of human healthy control inferior turbinate and glucocorticoid-treated, NSAID-exacerbated respiratory disease (N-ERD) nasal polyp nasal brushings
NSAID-exacerbated respiratory disease (N-ERD) represents a particularly severe endotype of chronic rhinosinusitis with nasal polyps (CRSwNP), which affects around 10-16% of CRSwNP patients. N-ERD is characterized by severe and refractory nasal polyposis, bronchial asthma and intolerance to non-stero...
ORGANISM(S): Homo sapiens 
2020-06-30 | E-MTAB-7962 | biostudies-arrayexpress
TranscriptomicsWhole-genome methylation profiling of monocytes and alveolar-like monocyte-derived macrophages from healthy controls and NSAID-exacerbated respiratory disease (N-ERD) patients
NSAID-exacerbated respiratory disease (N-ERD) represents a particularly severe endotype of chronic rhinosinusitis with nasal polyps (CRSwNP), which affects around 10-16% of CRSwNP patients. N-ERD is characterized by severe and refractory nasal polyposis, bronchial asthma and intolerance to non-stero...
ORGANISM(S): Homo sapiens 
2020-07-31 | E-MTAB-8065 | biostudies-arrayexpress
Genomicsuk10k_rare_neuromuscular_rel_2012_11_27-sc-20121218 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-11-27
EGAD00001000298 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2012_01_13-sc-20120611 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-01-13
EGAD00001000180 | EGA
Genomicsuk10k_rare_nmwg-rel-2013-03-06-sc-20140327 - samples
UK10K_RARE_NMWG REL-2013-03-06
EGAD00001000804 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2013_04_20-sc-20130522 - samples
UK10K_RARE_NEUROMUSCULAR REL-2013-04-20
EGAD00001000418 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2012_02_22-sc-20120613 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-02-22
EGAD00001000189 | EGA
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