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Gene Expression Analysis for Modelling Immune Trajectory and Endotype Transition During Pediatric Septic Shock We aimed to characterise the immune trajectory of 19 children with septic shock from first interaction with pediatric critical care teams (TP1) to 48 hours afterwards (TP2). We analysed da...
ORGANISM(S): Homo sapiens 
We developed a novel mouse model of acute bilirubin toxicity. 450mg/kg bilirubin was administered IP to mice, which exhibited transient hearing deficits and ataxia at 4 hours, and recovered by 24 hours. This toxicity is consistent with the human symptoms of bilirubin toxicity. To investigate the mol...
ORGANISM(S): Mus musculus 
We analysed data collected as part of the Biomarkers of Acute Serious Illness in Children (BASIC) study. BASIC was a prospective cohort study that enrolled critically ill children admitted to four PICUs in London and Eastern England, UK, during emergency transport by the Children’s Acute Transport S...
ORGANISM(S): Homo sapiens 
Targeted GC-MS detection of host and dietary metabolites and modifications by gut bacteria.
ORGANISM(S): Eggerthella Lenta (ncbitaxon:84112) Holdemania Filiformis (ncbitaxon:61171) Sutterella Wadsworthensis (ncbitaxon:40545) 
2023-11-03 | MSV000093291 | MassIVE
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