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UnknownmiR-155 in the progression of lung fibrosis in systemic sclerosis.
Not available
S-EPMC4932708 | biostudies-literature
TranscriptomicsTranscriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes
Trypanosoma cruzi infection is a major cause of cardiomyopathy. Gene profiling studies of hearts from infected mice have revealed prominent changes in gene expression within many functional pathways. This variety of transcriptomic changes in infected mice raises the question of whether gene express...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-17330 | biostudies-arrayexpress
UnknownExploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers <b>DS-103</b> as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties.
Not available
S-EPMC11867874 | biostudies-literature
GenomicsWhole genome sequencing of tumour and normal paired samples of diffuse intrinsic pontine gliomas
Diffuse intrinsic pontine glioma (DIPG) have a universally dismal prognosis (median 9-12 months), with neither chemotherapeutic nor targeted agents showing any substantial survival benefit in clinical trials in children with these tumours. DIPG are highly infiltrative malignant glial neoplasms of th...
EGAS00001000572 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:22:20:271-113 - samples
Whole exome sequencing of 6 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000706 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:02:33:112-168 - samples
Whole genome sequencing of 20 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000705 | EGA
GenomicsICR DIPG Data Access Committee
Data Access Committee EGAC00001000148
EGAC00001000148 | EGA
TranscriptomicsComparative genomic hybridization of high grade gliomas arising in children and young people
As genome-scale technologies begin to unravel the complexity of the equivalent tumours in adults, detailed characterisation of high grade gliomas in children have until recently been lacking. In order to validate and extend investigations of the differences between paediatric and adult tumours, we c...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-TABM-857 | biostudies-arrayexpress
TranscriptomicsCardiac gene expression and systemic cytokine profile are complementary in a murine model of post ischemic heart failure
After myocardial infarction (MI) activation of the immune system and inflammatory mechanisms, among others, can lead to ventricular remodeling and heart failure (HF). Interaction between these systemic alterations and corresponding changes in the heart has not been extensively examined in the settin...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-18703 | biostudies-arrayexpress
TranscriptomicsTherapy with bone marrow cells recovers gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy
Chronic chagasic cardiomyopathy is one of the leading causes of heart failure in Latin American countries, being associated with intense inflammatory response and fibrosis. We have previously shown that bone marrow mononuclear cell (BMC) transplantation improves inflammation, fibrosis and ventricula...
ORGANISM(S): Mus musculus 
2010-09-17 | E-GEOD-24088 | biostudies-arrayexpress
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