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UnknownImmunological repertoire linked to PSTPIP1-associated myeloid-related inflammatory (PAMI) syndrome.
Not available
S-EPMC8365952 | biostudies-literature
MetabolomicsReactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...
2019-05-22 | MTBLS593 | MetaboLights
UnknownBiotinidase deficiency: Genotype-biochemical phenotype association in Brazilian patients.
Not available
S-EPMC5428951 | biostudies-literature
TranscriptomicsSingle cell RNA sequencing of paired non small cell lung carcinoma tissue and peripheral blood from 5 donors
The immunosuppressive tumour microenvironment constitutes a significant hurdle to immune checkpoint inhibitors response. Both soluble factors and specialised immune cells such as regulatory T cells (TReg) are key components of active intratumoural immunosuppression. Previous studies have shown that ...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-9451 | biostudies-arrayexpress
TranscriptomicsRNA-seq of purified T cells treated with KY1044 + anti-CD3 against anti-CD3 treated controls
KY1044 is a human monoclonal IgG1 that selectively binds to Inducible T cell CO-stimulator (ICOS). The co-stimulatory effect of KY1044-stimulated human T cells was analysed by RNA sequencing (RNA seq). Purified pre-activated (ICOS+ve) T cells were stimulated with either KY1044 and anti-CD3 or anti-C...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-9500 | biostudies-arrayexpress
UnknownNewborn Screening for the Detection of the TP53 R337H Variant and Surveillance for Early Diagnosis of Pediatric Adrenocortical Tumors: Lessons Learned and Way Forward.
Not available
S-EPMC8656743 | biostudies-literature
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