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International Centre for Cancer Vaccine Science, University of Gdansk, Kladki 24, 80-822 Gdansk, Poland (1)
Regenerative Medicine Technologies Lab, Laboratories for Translational Research (LRT), Ente Ospedaliero Cantonale, Bellinzona (CH); Servizio di Ortopedia e Traumatologia, Ente Ospedaliero Cantonale, Lugano (CH); Euler Institute, Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano (CH) (1)

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Integrated microRNA and mRNA Signatures Associated with Survival in Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) includes basal and non-basal subclasses. To further stratify TNBC we determined microRNA (miRNA) and mRNA expression profiles, linked specific miRNA signatures to patient survival and used miRNA/mRNA anti-correlations to identify TNBC subclasses associated with e...

ORGANISM(S): Homo sapiens

2013-04-19 | E-GEOD-41970 | biostudies-arrayexpress

Opposing effects of cancer-type-specific SPOP mutations on BET protein degradation and sensitivity to BET inhibitors

Janouskova H, El Tekle G, Bellini E, Udeshi ND, Rinaldi A, Ulbricht A, Bernasocchi T, Civenni G, Losa M, Svinkina T, Bielski CM, Kryukov GV, Cascione L, Sara Napoli S, Enchev RI, Mutch DG, Carney ME, Berchuck A, Winterhoff BJN, Broaddus RR, Schraml P, Moch H, Bertoni F, Catapano CV, Peter M, Carr SA...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-12-16 | MSV000080401 | MassIVE

Dimethyl fumarate treatment shifts the immune environment toward an anti-inflammatory cell profile while maintaining protective humoral immunity.

Not available

S-EPMC8023410 | biostudies-literature

TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

Epithelial-to-mesenchymal transition (EMT) is a dynamic process that relies on cellular plasticity; an EMT/MET axis is critical for metastatic colonization of carcinomas. Unlike epithelial programming, regulation of mesenchymal programming is not well understood in EMT. Here we describe the first mi...

ORGANISM(S): Homo sapiens

2015-02-26 | E-GEOD-54505 | biostudies-arrayexpress

TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

Using a TWIST1-inducible epithelial-to-mesenchymal transition (EMT) model in HMLE cells, miRNA changes were profiled at different time points during an active EMT. This experiment includes a total of 12 samples consisting of 2 experimental groups at 2 matching time points (day 4, day 12), each with ...

ORGANISM(S): Homo sapiens

2015-02-26 | E-GEOD-58560 | biostudies-arrayexpress

HTGQC and shinyHTGQC: an R package and shinyR application for quality controls of HTG EDGE-seq protocols.

Not available

S-EPMC10027062 | biostudies-literature

The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type.

Not available

S-EPMC9400774 | biostudies-literature

Green Plasmonic Nanoparticles and Bio-Inspired Stimuli-Responsive Vesicles in Cancer Therapy Application.

Not available

S-EPMC7353186 | biostudies-literature

Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment.