Sort   by:  
 Page size 
TranscriptomicsLoss of lamin B1 results in prolongation of S-phase and decondensation of chromosome territories in the interphase nucleus of mammalian cells
Nuclear lamin B1 constitutes one of the major structural proteins in the lamina mesh. We silenced the expression of lamin B1 by RNA interference in the colon cancer cell line DLD-1 and showed a dramatic redistribution of H3K27me3 from the periphery to a more homogeneous nuclear dispersion; in additi...
ORGANISM(S): Homo sapiens 
2014-07-16 | E-GEOD-53546 | biostudies-arrayexpress
TranscriptomicsAneuploidy, oncogene amplification, and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells [CGH]
Human epithelial cancers are defined by a recurrent distribution of specific chromosomal aneuploidies. In our model system, mouse bladder and kidney epithelial cells spontaneously immortalize, transform and become tumorigenic after prolonged culture. We assessed genome and transcriptome alterations...
ORGANISM(S): Mus musculus 
2013-03-14 | E-GEOD-45128 | biostudies-arrayexpress
TranscriptomicsAneuploidy, oncogene amplification, and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-03-14 | E-GEOD-45129 | biostudies-arrayexpress
TranscriptomicsSystems-wide RNAi analysis of different chr13 genes in colorectal cancer cell line (SW480)
Expression profiles were generated for eight genes located on chromosome 13 following RNAi to enable the determination of gene specific LOF RNAi signatures in the colorectal cancer cell line SW480. Triplicate transfections of SW480 cells were performed using two different siRNA duplexes correspondin...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-33824 | biostudies-arrayexpress
Sort   by:  
 Page size