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TranscriptomicsDistinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation
The three-dimensional (3D) organization of the genome within the cell nucleus contributes to cell-specific gene expression in different cell types1. High-throughput 3CM-bM-^@M-^Sderived methods have revealed that the genome is segmented into contiguous topologically associating domains (TADs), which...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-53463 | biostudies-arrayexpress
Genomicsena-DATASET-Hospital Clinic Barcelona-13-08-2015-12:02:30:199-229 - samples
Whole Genome sequencing. 2 μg of genomic DNA from each sample was used for the construction of two short-insert paired-end sequencing libraries. Both types of libraries were sequenced in paired-end mode on Illumina GAIIx (2 × 151 bp) using Sequencing kit v4 or Illumina HiSeq2000 (2x101 bp) usi...
EGAD00001001466 | EGA
Genomicsena-DATASET-Hospital Clinic Barcelona-12-08-2015-11:33:40:243-146 - samples
Exome Sequencing. 3 μg of genomic DNA from each sample were sheared and used for the construction of a paired-end sequencing library as described in the paired-end sequencing sample preparation protocol provided by Illumina41. Enrichment of exonic sequences was then performed for each library usi...
EGAD00001001464 | EGA
GenomicsCDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.
Eukaryotic gene regulation implies that transcription factors gain access to genomic information via poorly understood processes involving activation and targeting of kinases, histone-modifying enzymes, and chromatin remodelers to chromatin. Here we report that progestin gene regulation in breast ca...
ORGANISM(S): Homo sapiens 
2014-01-08 | E-GEOD-53855 | biostudies-arrayexpress
Genomicsena-DATASET-BLUEPRINT-16-01-2015-10:49:23:886-135 - samples
RNAseq profile of purified plasma cells from multiple myeloma patients and tonsils of healthy donors
EGAD00001001212 | EGA
GenomicsBP_August_2015_RNA-Seq_plasma_cell_on_GRCh38 - samples
RNA-Seq data for 4 plasma cell sample(s). 4 run(s), 4 experiment(s), 4 alignment(s) on human genome GRCh38. Part of BLUEPRINT release August 2015. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20150820/homo_sapiens/README_rnaseq_analysis_crg_20150820
EGAD00001001523 | EGA
Genomicsena-DATASET-BLUEPRINT-16-03-2018-14:03:53:512-282 - samples
Analysis of the reference epigenomes and regulatory landscape of CLL as a whole and its major clinico-biological subtypes (with mutated and unmutated IGHV) in the light of the normal B-cell differentiation. We have extensively characterized the reference epigenomes of seven primary chronic lymphocy...
EGAD00001004046 | EGA
Genomicsmultiple_myeloma - samples
Purified plasma cells from bone marrow of Multiple myeloma patient
EGAD00010000672 | EGA
GenomicsBP_August_2016_RNA-Seq_Multiple_Myeloma_on_GRCh38 - samples
RNA-Seq data for 14 Multiple Myeloma sample(s). 14 run(s), 14 experiment(s), 14 analysis(s) on human genome GRCh38. Part of BLUEPRINT release August 2016. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20160816/homo_sapiens/README_rnaseq_analysis_crg_201608...
EGAD00001002401 | EGA
GenomicsBP_August_2015_RNA-Seq_Multiple_myeloma_on_GRCh38 - samples
RNA-Seq data for 11 Multiple myeloma sample(s). 11 run(s), 11 experiment(s), 11 alignment(s) on human genome GRCh38. Part of BLUEPRINT release August 2015. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20150820/homo_sapiens/README_rnaseq_analysis_crg_20150...
EGAD00001001471 | EGA
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