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TranscriptomicsRNA-seq of cardiac-specific Cdk1 knockout mice at 4 days after experimental myocardial infarction
Biological Relevance and Intent of the Experiment: The objective of this study is to elucidate the role of Cdk1 in cardiac function, specifically its contribution to cardiomyocyte (CM) proliferation and response to injury. Using a heart-specific Cdk1 knockout mouse model, we investigate the molecula...
ORGANISM(S): Mus musculus domesticus 
2024-10-31 | E-MTAB-14505 | biostudies-arrayexpress
TranscriptomicsRNA-seq of cardiac-specific Cdk1 knockout mice at 3 weeks after experimental myocardial infarction
Biological Relevance and Intent of the Experiment: The objective of this study is to elucidate the role of Cdk1 in cardiac function, specifically its contribution to cardiomyocyte proliferation and response to injury. Using a heart-specific Cdk1 knockout mouse model, we investigate the molecular and...
ORGANISM(S): Mus musculus domesticus 
2024-12-02 | E-MTAB-14508 | biostudies-arrayexpress
MetabolomicsHypoxia Dependent Inhibition of Glioblastoma Cell Proliferation, Invasion, and Metabolism by the Choline-Kinase Inhibitor JAS239
Background: Elevated choline kinase alpha (ChoK) levels are observed in most solid tumors, including glioblastomas (GBM), and ChoK inhibitors have demonstrated limited efficacy in GBM models. Given that hypoxia is associated with resistance to GBM therapy, we hypothesized that tumor hypoxia c...
2024-06-18 | MTBLS6212 | MetaboLights
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