Castration-resistance

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Director, Vancouver Prostate Centre Chief Executive Officer, PC-TRiADD Distinguished Professor and Head, Department of Urologic Sciences, UBC BC Leadership Chair in Prostate Cancer Research (1)
Faculty of Health Sciences, University of Macau, Taipa, Macau, China (1)
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Siteman Cancer Center Washington University in St. Louis (1)
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HIF1a inhibition overcomes castration resistance

PRJNA892463 | ENA

Impact of BCL2 Overexpression in castration resistance prostate cancer progression I

PRJNA1142951 | ENA

Cellular cartography reveals mouse prostate organization and determinants of castration resistance [multiome]

PRJNA1199986 | ENA

Expression data from docetaxel-resistant prostate cancer cell lines

Docetaxel-based chemotherapy is the standard first-line therapy in metastatic castration-resistant prostate cancer. However, most patients eventually develop resistance to this treatment. The aim of the study was to identify key molecular genes and networks associated with docetaxel resistance in 2 ...

ORGANISM(S): Homo sapiens

2012-01-01 | E-GEOD-33455 | biostudies-arrayexpress

Selective androgen receptor degrader (SARD) to overcome antiandrogen resistance in castration-resistant prostate cancer

Clinical resistance such as androgen receptor (AR) mutation, AR overexpression, and AR splice variants (ARVs) restrict the second-generation antiandrogens benefit in patients with castration-resistant prostate cancer (CRPC). Several strategies have been implemented to develop novel antiandrogens to ...

ORGANISM(S): Homo sapiens (Human)

2023-02-02 | PXD035721 | Pride